Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SORD | Q00796 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046502 | 1.00 | HSD11B1 (0.35) | HSD11B1CYP1A2CYP2D6GSK3BSORD | |
| SCHEMBL1202336 | 1.00 | HSD11B1 (0.35) | HSD11B1CYP1A2CYP2D6GSK3BSORD | |
| SCHEMBL12879545 | 0.93 | SORD (0.34) | SORDACACB | |
| SCHEMBL12879551 | 0.93 | SORD (0.34) | SORDACACB | |
| SCHEMBL3046737 | 0.89 | HTR3A (0.36) | TRPV3CDK1CCNE1CDK2 | |
| SCHEMBL3046733 | 0.89 | HTR3A (0.36) | TRPV3CDK1CCNE1CDK2 | |
| SCHEMBL8059391 | 0.83 | HSD11B1 (0.37) | HSD11B1CYP1A2CYP2D6GSK3BACACB | |
| SCHEMBL187793 | 0.81 | CCR1 (0.34) | CDK1 | |
| SCHEMBL7708685 | 0.81 | CCR1 (0.34) | CDK1 | |
| SCHEMBL12872295 | 0.81 | TRPV3 (0.39) | LMNATRPV3CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215093-B1 | NOVEL PIPERAZINO-DIHYDROTHIENOPYRIMIDINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2011-12-14 | — | — | EP | disclosed |