Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 11/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919099 | 1.00 | HTR5A (0.36) | HTR5AKDM4EGRM4SLC9A1SLC9A2 | |
| SCHEMBL16502851 | 0.87 | HTR5A (0.50) | HTR5ASLC9A1SLC9A2 | |
| SCHEMBL7921834 | 0.80 | MRGPRX4 (0.43) | KDM4EGRM4 | |
| SCHEMBL7913836 | 0.79 | KDM4E (0.36) | KDM4EGRM4 | |
| SCHEMBL16502745 | 0.79 | SLC6A3 (0.41) | KDM4EGRM4 | |
| SCHEMBL16502836 | 0.72 | HTR5A (0.53) | HTR5ASLC9A1 | |
| SCHEMBL16502829 | 0.72 | HTR5A (0.55) | HTR5ASLC9A1 | |
| SCHEMBL7911041 | 0.71 | F2 (0.35) | HTR5AKDM4EGRM4SLC9A1 | |
| SCHEMBL16494594 | 0.70 | HTR5A (0.66) | HTR5ASLC9A1 | |
| SCHEMBL12875073 | 0.68 | HTR5A (0.74) | HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394987-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2011-12-14 | — | — | EP | disclosed |