Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 5/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 5/20 | 0.32 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502745 | 0.88 | SLC6A3 (0.41) | KDM4ETTKGRM4ABL1DHODH | |
| SCHEMBL7918207 | 0.84 | PGK1 (0.33) | KDM4ETTKPGK1 | |
| SCHEMBL7921834 | 0.83 | MRGPRX4 (0.43) | KDM4EGRM4ABL1DHODHSLC6A3 | |
| SCHEMBL7915988 | 0.83 | HTR5A (0.39) | KDM4ETTKPGK1KRAS | |
| SCHEMBL7919099 | 0.79 | HTR5A (0.36) | KDM4EGRM4 | |
| SCHEMBL16503540 | 0.79 | HTR5A (0.36) | KDM4EGRM4 | |
| SCHEMBL16502851 | 0.78 | HTR5A (0.50) | — | |
| SCHEMBL7914783 | 0.74 | GABRG2 (0.34) | KDM4E | |
| SCHEMBL7913827 | 0.72 | ALOX15 (0.36) | KDM4EDHODH | |
| SCHEMBL16502675 | 0.72 | TP53 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |