Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.32 |
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917826 | 0.83 | PLA2G2D (0.46) | HTR5AHSD17B14CNR1CNR2 | |
| SCHEMBL7918750 | 0.79 | HTR5A (0.54) | HTR5A | |
| SCHEMBL7915822 | 0.74 | PLA2G2D (0.50) | HTR5A | |
| SCHEMBL7908906 | 0.73 | PLAU (0.34) | HTR5A | |
| SCHEMBL7918472 | 0.72 | HSD17B14 (0.36) | HSD17B14HSD17B1HSD17B2 | |
| SCHEMBL7915836 | 0.72 | GRM2 (0.35) | HTR5A | |
| SCHEMBL16494834 | 0.71 | HTR5A (0.61) | HTR5A | |
| SCHEMBL16502448 | 0.70 | MAPT (0.43) | HTR5A | |
| SCHEMBL16502418 | 0.69 | TTR (0.48) | HSD17B14 | |
| SCHEMBL16502660 | 0.69 | PLA2G2D (0.45) | HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394987-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2011-12-14 | — | — | EP | disclosed |