SCHEMBL16503760

SCHEMBL16503760

Cc1cc(C#N)cc(C(=O)NC(C)C)c1NC(=O)c1sc(Cn2nnc(C(F)(F)F)n2)nc1-c1ccccc1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 14/20 0.35
▸ SLC2A3 P11169 14/20 0.35
▸ SLC2A4 P14672 14/20 0.35
▸ SLC2A2 P11168 5/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ TSHR P16473 2/20 0.33
▸ POLB P06746 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ NPY1R P25929 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ NPY2R P49146 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ FNTA P49354 1/20 0.32
▸ FNTB P49356 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16503733 0.93 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL16503740 0.92 ALDH1A1 (0.35) ALDH1A1KMT2ATSHRHPGDHSD17B10
SCHEMBL16503737 0.92 HPGD (0.36) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL16503759 0.90 ALDH1A1 (0.34) ALDH1A1KMT2ATSHRMAPTHPGD
SCHEMBL16503763 0.86 EPAS1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL16503744 0.84 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL16503758 0.84 F10 (0.36) ALDH1A1KMT2APOLBMAPTHPGD
SCHEMBL16503762 0.83 HPGD (0.39) ALDH1A1KMT2ATSHRMEN1HPGD
SCHEMBL16503732 0.83 F10 (0.35) SLC2A1SLC2A3SLC2A4ALDH1A1HPGD
SCHEMBL16503727 0.82 MAPT (0.34) ALDH1A1POLBMAPTHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8980886-B2 Anthranilic acid derivatives BAYER CROPSCIENCE AG (DE) 2015-03-17 — — US disclosed
US-8980886-B2 Anthranilic acid derivatives BAYER CROPSCIENCE AG (DE) 2015-03-17 — — US disclosed
US-20110312953-A1 ANTHRANILIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-12-22 — — US disclosed
US-20110312953-A1 ANTHRANILIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312953-A1 ANTHRANILIC ACID DERIVATIVES ANTXR2, NQO2, ACLY SLC2A1 4190/4885SLC2A3 4342/4885SLC2A4 4481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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