Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 10/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332001 | 0.85 | AR (0.41) | ARNR1H2NR1H3MEN1ALOX15 | |
| SCHEMBL13095523 | 0.76 | GABRA1 (0.41) | ARNR1H2NR1H3MEN1ALOX15 | |
| SCHEMBL15459094 | 0.76 | AR (0.36) | ARNR1H2NR1H3MEN1ALOX15 | |
| SCHEMBL8586265 | 0.72 | NR1H2 (0.48) | ARNR1H2NR1H3MEN1ALOX15 | |
| SCHEMBL3661937 | 0.72 | NOTUM (0.46) | ARNR1H2NR1H3NOTUMMLYCD | |
| SCHEMBL15458957 | 0.72 | ALDH1A1 (0.37) | ARNR1H2NR1H3MEN1ALOX15 | |
| SCHEMBL22298248 | 0.70 | GABRA1 (0.37) | — | |
| SCHEMBL2031538 | 0.69 | CA1 (0.50) | ARNR1H2NR1H3MEN1ALOX15 | |
| SCHEMBL15463724 | 0.68 | NR1H2 (0.40) | ARNR1H2NR1H3MEN1ALOX15 | |
| SCHEMBL18698036 | 0.68 | NR1H2 (0.38) | ARNR1H2NR1H3MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395040-A1 | FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM | Central Glass Company, Limited (JP) | 2011-12-14 | — | — | EP | disclosed |