Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504154 | 0.93 | ELANE (0.32) | ELANEPOLBNPC1RAB9ACYP2C9 | |
| SCHEMBL13199224 | 0.93 | ELANE (0.39) | ESR1ESR2ELANEKDM4EPOLB | |
| SCHEMBL16504159 | 0.89 | PDE2A (0.33) | ELANEALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL16504152 | 0.84 | ELANE (0.45) | ELANE | |
| SCHEMBL807094 | 0.81 | ELANE (0.46) | ELANEKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL13801167 | 0.77 | ELANE (0.53) | ELANEALDH1A1 | |
| SCHEMBL13199223 | 0.77 | NPC1 (0.31) | ELANEPOLBNPC1RAB9ACYP2C9 | |
| SCHEMBL13199252 | 0.76 | PDE2A (0.35) | ELANEKDM4EMEN1KMT2AHTT | |
| SCHEMBL18056712 | 0.74 | MAPT (0.43) | ESR1ELANEKDM4EPOLBALDH1A1 | |
| SCHEMBL13063797 | 0.74 | ELANE (0.42) | ESR1ESR2ELANEKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395040-A1 | FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM | Central Glass Company, Limited (JP) | 2011-12-14 | — | — | EP | disclosed |