Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504170 | 0.89 | ESR1 (0.36) | ELANEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL13199252 | 0.87 | PDE2A (0.35) | PDE2AELANERXRARXRBRXRG | |
| SCHEMBL16504152 | 0.83 | ELANE (0.45) | ELANE | |
| SCHEMBL16504154 | 0.82 | ELANE (0.32) | ELANENPC1RAB9A | |
| SCHEMBL13199224 | 0.82 | ELANE (0.39) | ELANEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL807094 | 0.79 | ELANE (0.46) | ELANEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL15957710 | 0.77 | HSD11B1 (0.40) | PDE2AELANEHSD11B1GAAALDH1A1 | |
| SCHEMBL13801167 | 0.75 | ELANE (0.53) | ELANEALDH1A1 | |
| SCHEMBL17233803 | 0.74 | ELANE (0.51) | ELANEMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14701784 | 0.73 | ELANE (0.42) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395040-A1 | FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM | Central Glass Company, Limited (JP) | 2011-12-14 | — | — | EP | disclosed |