Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.59 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168902 | 0.85 | RAB9A (0.56) | KDM5AKDM4DKDM4CKDM5BKDM3A | |
| SCHEMBL3192352 | 0.85 | PKM (0.65) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16504728 | 0.84 | ALDH1A1 (0.49) | KDM5AKDM4DKDM4CKDM5BKDM3A | |
| SCHEMBL11163471 | 0.83 | SMN1; SMN2 (0.50) | KDM5AKDM4DKDM4CKDM5BKDM3A | |
| SCHEMBL13165575 | 0.83 | ALDH1A1 (0.67) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7547627 | 0.82 | ALDH1A1 (0.59) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11417747 | 0.82 | SMN1; SMN2 (0.59) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL693623 | 0.80 | PKM (0.54) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4055616 | 0.80 | TDP1 (0.57) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22374212 | 0.80 | PKM (0.54) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368027-B1 | METHODS OF TREATING PAIN OR FEVER USING PHARMACEUTICALLY ACTIVE ACETAMINOPHEN DIMERS LINKED THROUGH PHENOLIC HYDROXYL GROUPS | ORPHOMED INC (US) | 2022-03-02 | — | — | EP | disclosed |
| US-8071619-B2 | Injectable liquid formulation of paracetamol | NGUYEN-XUAN THO (CH) | 2011-12-06 | — | — | US | disclosed |