Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504459 | 0.85 | KDM5A (0.59) | RAB9AMAPTMAOASMN1; SMN2MEN1 | |
| SCHEMBL31198183 | 0.79 | HSD17B10 (0.59) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5674663 | 0.79 | HSD17B10 (0.59) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11163471 | 0.77 | SMN1; SMN2 (0.50) | RAB9AMAPTMAOASMN1; SMN2MEN1 | |
| SCHEMBL17736353 | 0.77 | NQO2 (0.57) | RAB9AMAPTMAOASMN1; SMN2MEN1 | |
| SCHEMBL9815484 | 0.75 | PKM (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29209949 | 0.74 | KDM4E (0.58) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7547627 | 0.73 | ALDH1A1 (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3192352 | 0.73 | PKM (0.65) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2611896 | 0.72 | ALB (0.61) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027679-B1 | SUBSTITUTED-5-((7-CHLORO-4-QUINOLINYL)AMINO)-3-(AMINO-METHYL)-(1,1'-BIPHENYL)-2-OL COMPOUNDS; PROCESSES FOR THEIR PRODUCTION; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1983-08-10 | — | — | EP | disclosed |
| EP-0027679-A2 | Substituted-5-((7-chloro-4-quinolinyl)amino)-3-(amino-methyl)-(1,1'-biphenyl)-2-ol compounds; processes for their production; and pharmaceutical compositions containing the compounds | WARNER-LAMBERT COMPANY (US) | 1981-04-29 | — | — | EP | disclosed |