SCHEMBL16508102

SCHEMBL16508102

CCCCCCCCCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)NC)[C@@H](C)CC

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 4/20 0.46
▸ GLP1R P43220 6/20 0.45
▸ NPY5R Q15761 4/20 0.44
▸ NPY4R P50391 4/20 0.44
▸ NPY1R P25929 3/20 0.44
▸ NPY2R P49146 1/20 0.44
▸ OPRM1 P35372 1/20 0.43
▸ OPRD1 P41143 1/20 0.43
▸ OPRK1 P41145 1/20 0.43
▸ PSMB5 P28074 2/20 0.42
▸ APLNR P35414 1/20 0.42
▸ GRIA1 P42261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16508132 0.94 NPY5R (0.48) F2NPY5RNPY4RNPY1RNPY2R
SCHEMBL16508044 0.92 PSMB5 (0.49) F2GLP1RPSMB5APLNR
SCHEMBL16507773 0.91 OPRM1 (0.49) F2GLP1RNPY5RNPY4RNPY1R
SCHEMBL16507772 0.90 APLNR (0.51) F2GLP1ROPRM1OPRD1OPRK1
SCHEMBL16507751 0.88 NPY5R (0.47) F2GLP1RNPY5RNPY4RNPY1R
SCHEMBL16507825 0.86 APLNR (0.53) F2GLP1RPSMB5APLNR
SCHEMBL16507946 0.85 GLP1R (0.50) F2GLP1RAPLNR
SCHEMBL16507936 0.85 GLP1R (0.50) F2GLP1RAPLNR
SCHEMBL16507962 0.85 APLNR (0.52) F2GLP1RPSMB5APLNR
SCHEMBL16507834 0.84 GLP1R (0.50) F2GLP1RAPLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR F2 4046/4885GLP1R 120/4885NPY5R 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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