Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.48 |
| ▸ | NPY4R | P50391 | 6/20 | 0.48 |
| ▸ | NPY1R | P25929 | 5/20 | 0.48 |
| ▸ | NPY2R | P49146 | 3/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508102 | 0.94 | F2 (0.46) | NPY5RNPY4RNPY1RNPY2RPSMB5 | |
| SCHEMBL16508566 | 0.90 | GRIA1 (0.48) | NPY5RNPY4RNPY1RNPY2RPSMB5 | |
| SCHEMBL16508044 | 0.88 | PSMB5 (0.49) | PSMB5APLNRMMP1F2 | |
| SCHEMBL16507772 | 0.87 | APLNR (0.51) | OPRM1OPRD1OPRK1APLNRF2 | |
| SCHEMBL16507773 | 0.86 | OPRM1 (0.49) | NPY5RNPY4RNPY1RNPY2RPSMB5 | |
| SCHEMBL16507961 | 0.85 | NPY4R (0.70) | NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL16507891 | 0.84 | NPY4R (0.57) | NPY5RNPY4RNPY1RNPY2RAPLNR | |
| SCHEMBL16508508 | 0.84 | GRIA1 (0.45) | NPY5RNPY4RNPY1RGRIA1MMP1 | |
| SCHEMBL16507845 | 0.84 | NPY4R (0.58) | NPY5RNPY4RNPY1RNPY2ROPRM1 | |
| SCHEMBL16507751 | 0.83 | NPY5R (0.47) | NPY5RNPY4RNPY1RNPY2ROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | ANTHOR THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | PTH1R, MC1R, CASR | NPY5R 1478/4885NPY4R 1387/4885NPY1R 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.