Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13758676 | 0.82 | TAAR1 (0.45) | TAAR1MAOBLOXL2DAO | |
| SCHEMBL3364178 | 0.78 | GFER (0.74) | TAAR1MAOBGFERLOXL2AOC3 | |
| SCHEMBL22504236 | 0.77 | TAAR1 (0.46) | TAAR1GFERPTGS1PTGS2DAO | |
| SCHEMBL7437052 | 0.75 | TAAR1 (0.68) | TAAR1MAOBGFERPTGS1PTGS2 | |
| SCHEMBL19877367 | 0.74 | LOXL2 (0.51) | LOXL2 | |
| SCHEMBL21653730 | 0.74 | CYP19A1 (0.36) | TAAR1GFERPTGS1PTGS2CYP19A1 | |
| SCHEMBL13577064 | 0.73 | TAAR1 (0.56) | TAAR1MAOBGFERPTGS1PTGS2 | |
| SCHEMBL20495035 | 0.72 | CYP19A1 (0.74) | TAAR1MAOBGFERPTGS1PTGS2 | |
| SCHEMBL1319643 | 0.72 | TAAR1 (0.73) | TAAR1MAOBLOXL2AOC3MAOA | |
| SCHEMBL5414 | 0.71 | TAAR1 (1.00) | TAAR1MAOBLOXL2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2436676-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-04-04 | — | — | EP | disclosed |