SCHEMBL1319643

SCHEMBL1319643

NCCCc1ccc(F)cc1

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.73
MAOB P27338 3/20 0.61
LOXL2 Q9Y4K0 1/20 0.56
MAOA P21397 2/20 0.50
AOC3 Q16853 2/20 0.48
HTR2A P28223 1/20 0.48
AOC2 O75106 1/20 0.47
HRH1 P35367 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2149447 0.98 TAAR1 (0.70) TAAR1MAOBLOXL2MAOAAOC3
SCHEMBL3706426 0.93 TAAR1 (0.70) TAAR1MAOBLOXL2MAOAAOC3
SCHEMBL21726316 0.91 TAAR1 (0.67) TAAR1MAOBLOXL2MAOAAOC3
SCHEMBL29263666 0.91 TAAR1 (0.67) TAAR1MAOBLOXL2MAOAAOC3
Hydrochloric Acid SCHEMBL7393435 0.91 TAAR1 (0.67) TAAR1MAOBLOXL2MAOAAOC3
SCHEMBL1567051 0.91 TAAR1 (0.67) TAAR1MAOBLOXL2MAOAAOC3
SCHEMBL7005631 0.91 TAAR1 (0.67) TAAR1MAOBLOXL2MAOAAOC3
SCHEMBL1091307 0.88 TAAR1 (0.57) TAAR1MAOBLOXL2
Oxalic Acid SCHEMBL31633764 0.88 TAAR1 (0.57) TAAR1MAOBLOXL2MAOAHTR2A
SCHEMBL3678682 0.87 MAOA (0.62) TAAR1LOXL2MAOAHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552838-A Amine dehydrogenase catalytic system, application thereof and eutectic solvent and preparation thereof 河北工业大学 2025-03-04 CN claimed
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-06-23 US claimed
CN-113512029-A Preparation and application of substituted pyrazole compound containing pyrimidinamine 沈阳中化农药化工研发有限公司 2021-10-19 CN claimed
WO-2020130592-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME 서울대학교산학협력단 2020-06-25 WO claimed
EP-1651605-B1 PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC (CA) 2012-05-02 EP claimed
EP-1651620-B1 PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC (CA) 2011-11-09 EP claimed
EP-1648874-B1 PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC (CA) 2011-10-05 EP claimed
EP-1846035-B1 COMBINATION THERAPY XENON PHARMACEUTICALS INC (CA) 2011-09-21 EP claimed
US-7763618-B2 1-Pentyl-3-{6-[4-(2-trifluoromethylbenzoyl)piperazin-1-yl]-pyridin-3-yl}urea; inhibitors of stearoyl-CoA desaturase; cardiovascular disease, diabetes, obesity, metabolic syndrome XENON PHARMACEUTICALS INC. (CA) 2010-07-27 US claimed
US-20100056460-A1 COMBINATION OF ORGANIC COMPOUNDS ALI MOHAMMED A 2010-03-04 US claimed
US-20050065143-A1 Pyridazine derivatives and their use as therapeutic agents XENON PHARMACEUTICALS INC. (CA) 2005-03-24 US claimed
WO-2005011655-A2 PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2005-02-10 WO claimed
WO-2005011654-A2 PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2005-02-10 WO claimed
WO-2005011657-A2 PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2005-02-10 WO claimed
US-20040082601-A1 Anti-inflammatory compounds SCOTT MALCOLM K (US) 2004-04-29 US claimed
US-20030171585-A1 Triphenylpropanamide compounds SCOTT MALCOLM K (US) 2003-09-11 US claimed
EP-0966430-A1 ANTI-INFLAMMATORY COMPOUNDS Ortho-Mcneil Pharmaceutical Corp. (US) 1999-12-29 EP claimed
WO-1999033786-A1 ANTI-INFLAMMATORY COMPOUNDS ORTHO-MCNEIL PHARMACEUTICAL CORPORATION (US) 1999-07-08 WO claimed
EP-0443573-A2 HIV protease inhibitors containing derived amino acids BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-08-28 EP claimed
EP-0443560-A2 HIV protease inhibitors BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-08-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194969-A1 METAL HALIDE PEROVSKITE LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME HCN4, SLC46A1, FES TAAR1 4232/4885MAOB 880/4885LOXL2 3274/4885
US-20040082601-A1 Anti-inflammatory compounds TNF, PTGES, PTGES2 TAAR1 3941/4885MAOB 2123/4885LOXL2 812/4885
US-20050065143-A1 Pyridazine derivatives and their use as therapeutic agents PRDX5, SNRPD3, SNRPD2 TAAR1 2591/4885MAOB 1042/4885LOXL2 1533/4885
US-20030171585-A1 Triphenylpropanamide compounds PTGES, PTGES2, MPO TAAR1 3293/4885MAOB 1445/4885LOXL2 2683/4885
US-20100056460-A1 COMBINATION OF ORGANIC COMPOUNDS REN, IAPP, ACE TAAR1 2579/4885MAOB 1331/4885LOXL2 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.