SCHEMBL16508015

SCHEMBL16508015

C=C[SiH](N[SiH3])c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270393 0.77 TSHR (0.33) ALDH1A1TSHR
SCHEMBL2274702 0.72 KCNN4 (0.32) ALDH1A1TSHR
SCHEMBL10867723 0.69 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL2101106 0.67 HTT (0.33)
SCHEMBL217350 0.67 TSHR (0.41) ALDH1A1TSHR
SCHEMBL2542387 0.67 TSHR (0.35) ALDH1A1TSHR
SCHEMBL1712669 0.67 TSHR (0.41) ALDH1A1TSHR
SCHEMBL2103682 0.66 CACNA2D1 (0.39) ALDH1A1TSHR
Fluoride SCHEMBL27718731 0.65 TSHR (0.39) ALDH1A1TSHR
SCHEMBL485788 0.64 ALDH1A1 (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150056394-A1 Coating Composition and Anti-Spatter Coating Formed Therefrom ND INDUSTRIES, INC. 2015-02-26 US disclosed
WO-2015027003-A1 COATING COMPOSITION AND ANTI-SPATTER COATING FORMED THEREFROM ND INDUSTRIES, INC. (US) 2015-02-26 WO disclosed