SCHEMBL217350

SCHEMBL217350

C=C[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
AKT1 P31749 1/20 0.33
ALOX15 P16050 1/20 0.31
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27718731 0.97 TSHR (0.39) TSHRALDH1A1AKT1ALOX15
SCHEMBL1712669 0.77 TSHR (0.41) TSHRALDH1A1AKT1ALOX15TGM2
SCHEMBL243791 0.72 TSHR (0.38) TSHRALDH1A1AKT1
SCHEMBL1066599 0.72 TSHR (0.38) TSHRALDH1A1AKT1ALOX15TGM2
SCHEMBL5049897 0.72 TSHR (0.38) TSHRALDH1A1AKT1
SCHEMBL16508016 0.72 TSHR (0.38) TSHRALDH1A1AKT1
SCHEMBL2270554 0.72 ALDH1A1 (0.38) TSHRALDH1A1AKT1
SCHEMBL7994863 0.72 TSHR (0.38) TSHRALDH1A1AKT1ALOX15TGM2
SCHEMBL10867723 0.72 ALDH1A1 (0.38) TSHRALDH1A1AKT1
SCHEMBL1493193 0.71 ALDH1A1 (0.32) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102597026-B Process and catalyst system for polydiene production BRIDGESTONE CORP 2014-11-26 CN claimed
CN-102597026-A Process and catalyst system for polydiene production BRIDGESTONE CORP 2012-07-18 CN claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7151106-B2 Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use NOVARTIS A.G. (CH) 2006-12-19 US claimed
EP-1259556-B1 IMPROVED DERIVATIVES OF SILANE FUNCTIONALIZED OLEFIN INTERPOLYMERS DOW GLOBAL TECHNOLOGIES INC (US) 2006-06-07 EP claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
JP-7097410-A None JP disclosed
US-12466850-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2025-11-11 US disclosed
US-12384861-B2 Crosslinked compositions from olefin/silane interpolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-12 US disclosed
CN-116171304-B Cross-linking compositions from olefin/silane interpolymers 陶氏环球技术有限责任公司 2025-05-23 CN disclosed
US-20250145795-A1 OLEFIN/SILANE INTERPOLYMER COMPOSITIONS WITH EXCELLENT THERMAL OXIDATION RESISTANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-08 US disclosed
US-20250136798-A1 OLEFIN/SILANE INTERPOLYMER COMPOSITIONS WITH REDUCED RESIDUAL ALDEHYDE AND/OR KETONE CONTENT DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-01 US disclosed
US-4728709-A Terminal cluster vinyl silicones and acrylate cluster silicones therefrom LOCTITE CORPORATION (US) 1988-03-01 US disclosed
EP-0186705-A1 TERMINAL CLUSTER ACRYLATE SILICONES. LOCTITE CORP (US) 1986-07-09 EP disclosed
US-4575545-A Terminal cluster acrylate silicones LOCTITE CORPORATION (US) 1986-03-11 US disclosed
US-4575546-A Terminal cluster vinyl silicones and acrylate cluster silicones therefrom LOCTITE CORPORATION (US) 1986-03-11 US disclosed
WO-1986000322-A1 TERMINAL CLUSTER ACRYLATE SILICONES LOCTITE CORPORATION (US) 1986-01-16 WO disclosed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US disclosed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466850-B2 Method for producing peptide compound VIP, NGLY1, NPR1 TSHR 288/4885ALDH1A1 4771/4885AKT1 3464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.