SCHEMBL1712669

SCHEMBL1712669

C=C[SiH](C=C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
AKT1 P31749 1/20 0.33
ALOX15 P16050 1/20 0.31
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217350 0.77 TSHR (0.41) TSHRALDH1A1AKT1ALOX15TGM2
Fluoride SCHEMBL27718731 0.74 TSHR (0.39) TSHRALDH1A1AKT1ALOX15
SCHEMBL5049897 0.72 TSHR (0.38) TSHRALDH1A1AKT1
SCHEMBL16508016 0.72 TSHR (0.38) TSHRALDH1A1AKT1
SCHEMBL1066599 0.72 TSHR (0.38) TSHRALDH1A1AKT1ALOX15TGM2
SCHEMBL10867723 0.72 ALDH1A1 (0.38) TSHRALDH1A1AKT1
SCHEMBL2270554 0.72 ALDH1A1 (0.38) TSHRALDH1A1AKT1
SCHEMBL243791 0.72 TSHR (0.38) TSHRALDH1A1AKT1
SCHEMBL7994863 0.72 TSHR (0.38) TSHRALDH1A1AKT1ALOX15TGM2
SCHEMBL29249747 0.71 ALDH1A1 (0.41) ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2881408-B1 Styrene-based copolymer and thermoplastic resin composition including the same LOTTE ADVANCED MAT CO LTD (KR) 2017-09-20 EP claimed
US-9365671-B2 Styrene-based copolymer and thermoplastic resin composition including the same SAMSUNG SDI CO., LTD. (KR) 2016-06-14 US claimed
EP-2881408-A1 Styrene-based copolymer and thermoplastic resin composition including the same Samsung SDI Co., Ltd. (KR) 2015-06-10 EP claimed
CN-104693334-A Styrene-based copolymer and thermoplastic resin composition including the same SAMSUNG SDI CO LTD 2015-06-10 CN claimed
US-20150152205-A1 Styrene-Based Copolymer and Thermoplastic Resin Composition Including the Same LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2015-06-04 US claimed
US-8449868-B2 Preparation of cationic nanoparticles and personal care compositions comprising said nanoparticles BASF SE (DE) 2013-05-28 US claimed
CN-102112100-A Preparation of cationic nanoparticles and personal care compositions containing the same BASF SE 2011-06-29 CN claimed
EP-2254545-A2 PREPARATION OF CATIONIC NANOPARTICLES AND PERSONAL CARE COMPOSITIONS COMPRISING SAID NANOPARTICLES BASF SE (DE) 2010-12-01 EP claimed
US-20090214447-A1 Preparation of cationic nanoparticles and personal care compositions comprising said nanoparticles BASF SE (DE) 2009-08-27 US claimed
WO-2009103651-A2 PREPARATION OF CATIONIC NANOPARTICLES AND PERSONAL CARE COMPOSITIONS COMPRISING SAID NANOPARTICLES BASF SE (DE) 2009-08-27 WO claimed
CN-1384123-A Synthesis of polymer and film of the polymer HIPRAY CO (US) 2002-12-11 CN claimed
EP-1245586-A2 Polymer synthesis and films therefrom Shipley Co. L.L.C. (US) 2002-10-02 EP claimed
US-6420441-B1 DISPERSING REMOVABLE CROSSLINKED POLYMER POROGENS IN A POLYSILOXANE, CURING, AND HEATING TO REMOVE POROGEN; LOW DIELECTRIC CONSTANT; HIGH POROSITY; INSULATION MATERIALS SHIPLEY COMPANY, L.L.C. 2002-07-16 US claimed
US-20020065331-A1 Antireflective porogens SHIPLEY COMPANY, L.L.C. 2002-05-30 US claimed
CN-1347932-A Porous material CYPRI INC (US) 2002-05-08 CN claimed
EP-1197998-A2 Antireflective porogens Shipley Company LLC (US) 2002-04-17 EP claimed
EP-1172823-A1 Porous materials Shipley Company LLC (US) 2002-01-16 EP claimed
US-6271273-B1 Porous materials SHIPLEY COMPANY, L.L.C. 2001-08-07 US claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090214447-A1 Preparation of cationic nanoparticles and personal care compositions comprising said nanoparticles CUTA, ARG1, ARG2 TSHR 3371/4885ALDH1A1 3471/4885AKT1 3061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.