SCHEMBL16508123

SCHEMBL16508123

CSCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(N)=O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 1/20 0.38
▸ CCKBR P32239 3/20 0.38
▸ CTSL P07711 3/20 0.37
▸ CTSS P25774 3/20 0.37
▸ CTSK P43235 3/20 0.37
▸ CTSH P09668 1/20 0.37
▸ GRPR P30550 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12045120 0.91 REN (0.41) RENCTSLCTSSCTSKCTSH
SCHEMBL30999518 0.84 CCKBR (0.46) CCKBR
SCHEMBL30074450 0.83 REN (0.37) RENCCKBR
SCHEMBL30999648 0.83 CCKBR (0.62) CCKBR
SCHEMBL27624719 0.83 MMP7 (0.38) RENGRPR
SCHEMBL31157683 0.83 CTSL (0.51) CCKBRCTSLCTSSCTSKCTSH
SCHEMBL11759100 0.82 REN (0.54) RENCTSLCTSSCTSK
SCHEMBL11765581 0.82 REN (0.54) RENCTSLCTSSCTSK
SCHEMBL12972180 0.82 MMP7 (0.38) RENGRPR
SCHEMBL16507899 0.81 PTPN1 (0.44) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR REN 525/4885CCKBR 1309/4885CTSL 2848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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