SCHEMBL16508951

SCHEMBL16508951

CN(C)c1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)C(O)[C@@H]2O)c(=O)[nH]1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 7/20 0.66
IMPDH1 P20839 2/20 0.66
TGM2 P21980 1/20 0.64
P2RX3 P56373 3/20 0.64
TAS1R3 Q7RTX0 1/20 0.63
TAS1R1 Q7RTX1 1/20 0.63
ENPP1 P22413 2/20 0.62
P2RY1 P47900 2/20 0.62
P2RY12 Q9H244 2/20 0.62
P2RX1 P51575 1/20 0.61
P2RY6 Q15077 1/20 0.61
P2RY11 Q96G91 1/20 0.61
P2RX4 Q99571 1/20 0.61
FUT5 Q11128 1/20 0.59
NT5E P21589 2/20 0.59
KRAS P01116 2/20 0.58
RNASEL Q05823 1/20 0.58
P2RX2 Q9UBL9 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18574074 0.99 P2RX3 (0.65) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL30363045 0.99 P2RX3 (0.65) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL14946399 0.99 P2RX3 (0.65) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL14929515 0.99 P2RX3 (0.65) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL263726 0.93 IMPDH2 (0.75) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL14929355 0.89 IMPDH2 (0.64) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL18574075 0.89 IMPDH2 (0.64) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL14946391 0.89 IMPDH2 (0.64) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL18269536 0.88 P2RX3 (0.68) IMPDH2IMPDH1TGM2P2RX3TAS1R3
SCHEMBL18289612 0.88 P2RX3 (0.68) IMPDH2IMPDH1TGM2P2RX3TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9067964-B2 Complex and method for enhancing nuclear delivery OLIGOMER SCIENCES AB (SE) 2015-06-30 US disclosed
US-20110306138-A1 COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY OLIGOMER SCIENCES AB (SE) 2011-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110306138-A1 COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY SNRPE, SNRPA, HNRNPH3 IMPDH2 1756/4885IMPDH1 2006/4885TGM2 1855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.