Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NMT1 | P30419 | 14/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509593 | 0.84 | LMNA (0.61) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 | |
| SCHEMBL18903932 | 0.82 | BCHE (0.43) | LMNAHTTNMT1 | |
| SCHEMBL16503024 | 0.81 | NMT1 (0.69) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 | |
| SCHEMBL16503023 | 0.78 | SMN1; SMN2 (0.61) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 | |
| SCHEMBL16509534 | 0.77 | NMT1 (0.60) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 | |
| SCHEMBL16509495 | 0.76 | FFAR4 (0.60) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 | |
| SCHEMBL16503036 | 0.75 | LMNA (0.61) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 | |
| SCHEMBL16509596 | 0.75 | NMT1 (0.57) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 | |
| SCHEMBL16502941 | 0.74 | LMNA (1.00) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 | |
| SCHEMBL13457978 | 0.74 | LMNA (0.66) | LMNAHTTSMN1; SMN2NMT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828346-B2 | N-myristoyl transferase inhibitors | UNIVERSITY OF DUNDEE (GB) | 2017-11-28 | — | — | US | disclosed |
| US-20160060224-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | UNIVERSITY OF DUNDEE (GB) | 2016-03-03 | — | — | US | disclosed |
| US-9156811-B2 | N-myristoyl transferase inhibitors | Univeristy of Dundee (GB) | 2015-10-13 | — | — | US | disclosed |
| US-20110312921-A1 | N-Myristoyl Transferase Inhibitors | DUNDEE, UNIVERSITY OF (GB) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312921-A1 | N-Myristoyl Transferase Inhibitors | GNMT, NNMT, SPTLC1 | LMNA 4097/4885HTT 1540/4885SMN1; SMN2 3634/4885 |
| US-20160060224-A1 | N-MYRISTOYL TRANSFERASE INHIBITORS | GNMT, NNMT, SPTLC1 | LMNA 4097/4885HTT 1540/4885SMN1; SMN2 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.