SCHEMBL16511925

SCHEMBL16511925

COc1ccc2ccc3ccc(OC)nc3c2n1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 14/20 0.44
MTNR1B P49286 14/20 0.44
CCR1 P32246 1/20 0.43
RAB9A P51151 1/20 0.43
CCR5 P51681 1/20 0.43
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SIRT2 Q8IXJ6 1/20 0.41
SIRT1 Q96EB6 1/20 0.41
NNMT P40261 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
HTR2C P28335 2/20 0.40
CLK1 P49759 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16511929 0.87 MTNR1A (0.41) MTNR1AMTNR1BCCR1RAB9ACCR5
SCHEMBL12112562 0.85 PARP1 (0.44) MTNR1AMTNR1BRAB9AKMT2AHTR2C
SCHEMBL11379744 0.83 LMNA (0.61) MTNR1AMTNR1BCCR1RAB9ACCR5
SCHEMBL13865283 0.82 KMT2A (0.42) MTNR1AMTNR1BCCR1RAB9ACCR5
SCHEMBL15648746 0.80 MCHR1 (0.65) MTNR1AMTNR1BRAB9AKMT2A
SCHEMBL12507362 0.80 MTNR1A (0.50) MTNR1AMTNR1BCYP1A2KMT2A
SCHEMBL18544257 0.80 MTNR1A (0.47) MTNR1AMTNR1BRAB9AKMT2ACLK1
SCHEMBL1408392 0.80 MAPT (0.47) MTNR1AMTNR1BPOLBTDP1KMT2A
SCHEMBL12112699 0.79 CYP1A2 (0.40) MTNR1AMTNR1BCCR1RAB9ACCR5
SCHEMBL2819275 0.79 PTGS2 (0.37) MTNR1AMTNR1BPOLBTDP1NNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-111718381-A Osmium metal organic compound containing polypyridine ligand and preparation method and application thereof 荆楚理工学院 2020-09-29 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
EP-4735170-A1 METATHESIS COMPOSITIONS COMPRISING AIR-STABLE IMIDO ALKYLIDENE COMPLEXES Verbio SE (DE) 2026-05-06 EP disclosed
WO-2025003441-A1 METATHESIS COMPOSITIONS COMPRISING AIR-STABLE IMIDO ALKYLIDENE COMPLEXES VERBIO VEREINIGTE BIOENERGIE AG (DE) 2025-01-02 WO disclosed
CN-111518145-B Cyano-bridged metal organic compound with intramolecular magnetic transformation and preparation method and application thereof 荆楚理工学院 2023-06-20 CN disclosed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US disclosed
CN-111718381-A Osmium metal organic compound containing polypyridine ligand and preparation method and application thereof 荆楚理工学院 2020-09-29 CN disclosed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN disclosed
WO-2011152358-A1 MEMBRANE CONTAINING SILVER COMPLEX 住友化学株式会社 (JP) 2011-12-08 WO disclosed