Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382539 | 0.84 | TDP1 (0.46) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL2367986 | 0.84 | TDP1 (0.46) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL14339786 | 0.84 | ALDH1A1 (0.36) | ALDH1A1HPGDTSHREPRS1 | |
| SCHEMBL9237623 | 0.71 | POLB (0.45) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL19465429 | 0.71 | KDM4E (0.39) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL31288526 | 0.70 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDRECQLTDP1 | |
| SCHEMBL221824 | 0.70 | TRPA1 (0.39) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL3363162 | 0.70 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDRECQLTDP1 | |
| SCHEMBL3033935 | 0.70 | GABRA1 (0.33) | ALDH1A1HPGDRECQLTDP1ALOX15 | |
| SCHEMBL5872088 | 0.70 | ALOX15 (0.39) | KDM4EALDH1A1HPGDRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962779-B2 | Method of forming polyaryl polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-02-24 | — | — | US | disclosed |