Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653001 | 0.78 | GPR35 (0.43) | ALDH1A1KDM4EGPR35RAB9AHTT | |
| SCHEMBL28129418 | 0.77 | BCL9 (0.40) | ALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL1654192 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GPR35L3MBTL1POLB | |
| SCHEMBL1653790 | 0.76 | KMT2A (0.53) | ALDH1A1KDM4ERAB9AHTTNPC1 | |
| SCHEMBL1653798 | 0.76 | GPR35 (0.45) | ALDH1A1KDM4EGPR35RAB9AHTT | |
| SCHEMBL1653846 | 0.74 | GPR35 (0.39) | ALDH1A1KDM4EGPR35RAB9AHTT | |
| SCHEMBL7782152 | 0.74 | SLC1A3 (0.37) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL7782151 | 0.74 | SLC1A3 (0.37) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11220084 | 0.73 | MMP2 (0.41) | ALDH1A1KDM4EGPR35RAB9AL3MBTL1 | |
| SCHEMBL3031094 | 0.73 | MMP2 (0.41) | ALDH1A1KDM4EGPR35RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092557-A1 | Neuraminidase Inhibitors And Compositions And Methods Related Thereto | INFLUMEDIX INC. (US) | 2011-04-21 | — | — | US | claimed |
| US-20110092557-A1 | Neuraminidase Inhibitors And Compositions And Methods Related Thereto | INFLUMEDIX INC. (US) | 2011-04-21 | — | — | US | disclosed |
| EP-0444068-A1 | TRIALKYSILYL ESTERS OF AMINO ACIDS AND THEIR USE IN THE SYNTHESIS OF PEPTIDES | PUBLIC HEALTH LABORATORY SERVICE BOARD (GB) | 1991-09-04 | — | — | EP | disclosed |
| WO-1990005738-A1 | TRIALKYSILYL ESTERS OF AMINO ACIDS AND THEIR USE IN THE SYNTHESIS OF PEPTIDES | PUBLIC HEALTH LABORATORY SERVICE BOARD (GB) | 1990-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092557-A1 | Neuraminidase Inhibitors And Compositions And Methods Related Thereto | NEU1, DAO, NEU3 | ALDH1A1 2018/4885KDM4E 2909/4885GPR35 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.