SCHEMBL3557147

SCHEMBL3557147

O=[N+]([O-])n1c2ccccc2c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
GPR3 P46089 1/20 0.42
LMNA P02545 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
POLB P06746 2/20 0.40
ATM Q13315 2/20 0.40
ALDH1A1 P00352 4/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
TLR9 Q9NR96 2/20 0.40
XBP1 P17861 1/20 0.40
PAX8 Q06710 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2768225 0.82 MAOA (0.40) MAPTALDH1A1SMN1; SMN2KDM4EHTT
SCHEMBL31326012 0.80 ALDH1A1 (0.41) MAPTLMNAMEN1KMT2ACYP2C19
SCHEMBL11876810 0.77 HSD17B10 (0.38) MAPTLMNAMEN1KMT2ACYP1A2
SCHEMBL1653137 0.76 MAPT (0.40) MAPTLMNAMEN1KMT2AATM
SCHEMBL7245000 0.74 MAPT (0.38) MAPTLMNAMEN1KMT2ACYP1A2
SCHEMBL10733718 0.74 MEN1 (0.33) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL7250388 0.73 TP53 (0.50) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL2035587 0.71 HTR6 (0.43) MAPTLMNAMEN1KMT2ACYP1A2
Nitric Acid SCHEMBL31591113 0.71 GPR3 (0.67) MAPTGPR3LMNAMEN1KMT2A
SCHEMBL1051084 0.69 CA12 (0.50) MAPTLMNAKMT2ACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119882120-A Polarizing plate complex and image display device 住友化学株式会社 2025-04-25 CN disclosed
EP-3416948-B1 INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS UNIV QUEENSLAND (AU) 2024-07-24 EP disclosed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 US disclosed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 US disclosed
CN-109071454-B Sulfonylureas and related compounds and uses thereof 昆士兰大学 2023-02-17 CN disclosed
CN-109154686-B Resin laminate with polarizing plate and display device comprising same 住友化学株式会社 2021-12-24 CN disclosed
US-20200299284-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME INFLAZOME LIMITED (IE) 2020-09-24 US disclosed
CN-109153894-B Resin laminate with transparent adhesive and display device comprising same 住友化学株式会社 2020-04-07 CN disclosed
EP-3416948-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University Of Queensland (AU) 2018-12-26 EP disclosed
WO-2017140778-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME THE UNIVERSITY OF QUEENSLAND (AU) 2017-08-24 WO disclosed
US-20050187284-A1 Integrin receptor inhibitors GENENTECH, INC. (US) 2005-08-25 US disclosed
US-6933314-B2 Integrin receptor inhibitors GENENTECH, INC. (US) 2005-08-23 US disclosed
US-20040077693-A1 Integrin receptor inhibitors GENENTECH, INC. 2004-04-22 US disclosed
US-6706753-B2 2-AMINO-FLUORENE DERIVATIVES USEFUL FOR PROPHYLACTIC AND/OR THERAPEUTIC TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH ALPHA 4 INTERGRINS OR THEIR LIGANDS GENENTECH, INC. 2004-03-16 US disclosed
EP-1330430-A2 INTEGRIN RECEPTOR INHIBITORS GENENTECH, INC. (US) 2003-07-30 EP disclosed
US-20030100599-A1 2-amino-fluorene derivatives useful for prophylactic and/or therapeutic treatment of diseases and conditions associated with alpha 4 intergrins or their ligands GENENTECH, INC. 2003-05-29 US disclosed
US-20020035104-A1 Integrin receptor inhibitors GENENTECH, INC. 2002-03-21 US disclosed
WO-2002016313-A2 INTEGRIN RECEPTOR INHIBITORS GENENTECH, INC. (US) 2002-02-28 WO disclosed
US-4300900-A WITH A WATER INSOLUBLE DYE, A DISPERSING AGENT AND A METAL COMPLEX MIXTURE CIBA-GEIGY CORPORATION (US) 1981-11-17 US disclosed
US-4211527-A Process for dyeing polyester materials CIBA-GEIGY CORPORATION (US) 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077693-A1 Integrin receptor inhibitors ITGB1, ITGA1, ITGA4 MAPT 4730/4885GPR3 395/4885LMNA 1868/4885
US-11858922-B2 Sulfonylureas and related compounds and use of same NLRP3, NOD1, PYCARD MAPT 3536/4885GPR3 181/4885LMNA 1252/4885
US-20020035104-A1 Integrin receptor inhibitors ITGB1, ITGA1, ITGA4 MAPT 4730/4885GPR3 395/4885LMNA 1868/4885
US-20050187284-A1 Integrin receptor inhibitors ITGA4, ITGB4, ITGB1 MAPT 4495/4885GPR3 597/4885LMNA 1600/4885
US-20030100599-A1 2-amino-fluorene derivatives useful for prophylactic and/or therapeutic treatment of diseases and conditions associated with alpha 4 intergrins or their ligands ITGA1, ITGA2, ITGB1 MAPT 4867/4885GPR3 238/4885LMNA 1173/4885
US-20200299284-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, NOD1, PYCARD MAPT 3536/4885GPR3 181/4885LMNA 1252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.