Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL156613 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1151273 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL17667155 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9704612-B2 | Composition of silver-conjugated compound composite | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-07-11 | — | — | US | claimed |
| EP-2687304-B1 | METAL COMPLEX COMPOSITIONS AND MIXTURE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-01-23 | — | — | EP | disclosed |
| US-9704612-B2 | Composition of silver-conjugated compound composite | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-07-11 | — | — | US | disclosed |
| EP-2687304-A1 | METAL COMPLEX COMPOSITIONS AND MIXTURE THEREOF | Sumitomo Chemical Company Limited (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140001422-A1 | COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-02 | — | — | US | disclosed |
| US-20130341571-A1 | METALLIC COMPOSITE COMPOSITION AND MIXTURE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-26 | — | — | US | disclosed |
| US-20060128608-A1 | Novel chemical compounds and their use | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2006-06-15 | — | — | US | disclosed |
| US-20030176610-A1 | Poly(methylene/polyethylene terephthalate) copolymers | BAYLOR UNIVERSITY | 2003-09-18 | — | — | US | disclosed |
| US-6011133-A | Laminates of glass or metal and poly(alkylene dicarboxylates) and syntheses thereof | BAYLOR UNIVERSITY (US) | 2000-01-04 | — | — | US | disclosed |
| US-5837381-A | MULTILAYER PROTECTIVE COATING; WEAR AND CORROSION RESISTANCE | UNIV BAYLOR (US) | 1998-11-17 | — | — | US | disclosed |
| US-5668224-A | TETRAALKYL- OR TRIALKYLAMMONIUM END GROUPS | BAYLOR UNIVERSITY | 1997-09-16 | — | — | US | disclosed |
| US-5451643-A | PROTECTIVE COATINGS FOR METALS OR GLASS | BAYLOR UNIVERSITY (US) | 1995-09-19 | — | — | US | disclosed |
| WO-1994020296-A1 | POLY (ALKYLENE DICARBOXYLATES) AND SYNTHESES THEREOF | BAYLOR UNIVERSITY (US) | 1994-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | PGLS, ABCG2, UGCG | TSHR 4534/4885TP53 2032/4885SRD5A2 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.