Norleucine

Norleucine

SCHEMBL1655261

C=C(C)C(=O)O.CCCCC(N)C(=O)O

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 2/20 0.55
SLC1A1 P43005 2/20 0.55
SLC1A3 P43003 1/20 0.55
DDAH1 O94760 3/20 0.50
NOS1 P29475 6/20 0.49
NOS2 P35228 5/20 0.49
NOS3 P29474 3/20 0.49
GRIK1 P39086 3/20 0.49
GRIK2 Q13002 2/20 0.49
MEN1 O00255 1/20 0.49
CYP2C19 P33261 1/20 0.49
KMT2A Q03164 1/20 0.49
GSR P00390 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
BLM P54132 1/20 0.46
DPP7 Q9UHL4 1/20 0.44
SLC15A1 P46059 1/20 0.44
NOD1 Q9Y239 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Norleucine SCHEMBL17240908 0.88 SLC1A2 (0.62) SLC1A2SLC1A1SLC1A3DDAH1NOS1
Norleucine SCHEMBL5707528 0.88 SLC1A2 (0.62) SLC1A2SLC1A1SLC1A3DDAH1NOS1
Norleucine SCHEMBL198127 0.88
Norleucine SCHEMBL5497693 0.88 SLC1A2 (0.67) SLC1A2SLC1A1SLC1A3DDAH1NOS1
Norleucine SCHEMBL8393 0.88
Norleucine SCHEMBL5051846 0.88 SLC1A2 (0.67) SLC1A2SLC1A1SLC1A3DDAH1NOS1
Norleucine SCHEMBL26474 0.88 SLC1A2 (0.67) SLC1A2SLC1A1SLC1A3DDAH1NOS1
Norleucine SCHEMBL2785913 0.88 SLC1A2 (0.67) SLC1A2SLC1A1SLC1A3DDAH1NOS1
Norleucine SCHEMBL8392 0.88
Norleucine SCHEMBL6055486 0.86 SLC1A2 (0.60) SLC1A2SLC1A1SLC1A3DDAH1NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102112222-A Hazardous substance removing material and method for removing hazardous substance FUJIFILM CORP 2011-06-29 CN disclosed
US-20110150960-A1 HAZARDOUS SUBSTANCE REMOVING MATERIAL AND METHOD FOR REMOVING HAZARDOUS SUBSTANCE FUJIFILM CORPORATION (JP) 2011-06-23 US disclosed
EP-2307134-A1 HAZARDOUS SUBSTANCE REMOVING MATERIAL AND METHOD FOR REMOVING HAZARDOUS SUBSTANCE FUJIFILM Corporation (JP) 2011-04-13 EP disclosed
WO-2010013833-A1 HAZARDOUS SUBSTANCE REMOVING MATERIAL AND METHOD FOR REMOVING HAZARDOUS SUBSTANCE FUJIFILM CORPORATION (JP) 2010-02-04 WO disclosed
US-20100028369-A1 Hazardous substance removing material and method for removing hazardous substance FUJIFILM CORPORATION (JP) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110150960-A1 HAZARDOUS SUBSTANCE REMOVING MATERIAL AND METHOD FOR REMOVING HAZARDOUS SUBSTANCE FCGR1A, FCGR2A, FCGR3B SLC1A2 675/4885SLC1A1 650/4885SLC1A3 782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.