Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554273 | 0.78 | NNMT (0.33) | FBP1ALDH1A1 | |
| SCHEMBL359159 | 0.75 | SMN1; SMN2 (0.43) | XIAPBIRC2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3718331 | 0.75 | SMN1; SMN2 (0.43) | XIAPBIRC2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9641232 | 0.74 | SMN1; SMN2 (0.42) | XIAPBIRC2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20898577 | 0.72 | ELANE (0.43) | RAB9A | |
| SCHEMBL16553709 | 0.68 | — | — | |
| SCHEMBL9668770 | 0.66 | ELANE (0.40) | — | |
| SCHEMBL17933365 | 0.66 | FDPS (0.38) | FDPS | |
| SCHEMBL17933345 | 0.66 | FDPS (0.38) | FDPS | |
| SCHEMBL17132071 | 0.66 | UHRF1 (0.46) | FDPSALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10053476-B2 | Phosphohistidine and phosphotyrosine analogues | UNIVERSITY OF SHEFFIELD (GB) | 2018-08-21 | — | — | US | disclosed |
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
| EP-2976346-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | University of Sheffield (GB) | 2016-01-27 | — | — | EP | disclosed |
| WO-2015033120-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2015-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | HRH3, CYTH3, CYTH2 | FDPS 3192/4885FBP1 1675/4885XIAP 1632/4885 |
| US-10053476-B2 | Phosphohistidine and phosphotyrosine analogues | HRH3, CYTH3, CYTH2 | FDPS 3105/4885FBP1 1547/4885XIAP 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.