Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554480 | 0.89 | MEN1 (0.49) | SMN1; SMN2NPC1RAB9AGAAKAT6A | |
| SCHEMBL16554515 | 0.89 | RAB9A (0.54) | SMN1; SMN2NPC1RAB9AKMT2APOLB | |
| SCHEMBL16554719 | 0.88 | PTGS2 (0.53) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL16554555 | 0.87 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9AKMT2ACTDSP1 | |
| SCHEMBL16554452 | 0.87 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9AKAT6AKMT2A | |
| SCHEMBL16554529 | 0.87 | PTGS2 (0.47) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL16554423 | 0.86 | MEN1 (0.49) | SMN1; SMN2NPC1RAB9AGAAKAT6A | |
| SCHEMBL16554488 | 0.85 | RAB9A (0.47) | SMN1; SMN2NPC1RAB9AKAT6AKMT2A | |
| SCHEMBL16554310 | 0.85 | KMT2A (0.51) | SMN1; SMN2NPC1RAB9AGAAKAT6A | |
| SCHEMBL16554440 | 0.85 | MEN1 (0.51) | SMN1; SMN2NPC1RAB9AKAT6AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | claimed |
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | disclosed |