Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.49 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554488 | 0.93 | RAB9A (0.47) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16554480 | 0.91 | MEN1 (0.49) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16554400 | 0.89 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL16554719 | 0.89 | PTGS2 (0.53) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16554440 | 0.89 | MEN1 (0.51) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16554555 | 0.88 | RAB9A (0.49) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16554452 | 0.88 | NPC1 (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16554841 | 0.88 | GAA (0.49) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16554423 | 0.87 | MEN1 (0.49) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16554310 | 0.86 | KMT2A (0.51) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | claimed |
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | disclosed |