Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16565820 | 1.00 | BACE1 (0.34) | BACE1CYP11B2CYP11B1USP14 | |
| SCHEMBL16565850 | 0.86 | TRPA1 (0.34) | — | |
| SCHEMBL16554594 | 0.86 | TRPA1 (0.34) | — | |
| SCHEMBL16565819 | 0.84 | — | — | |
| SCHEMBL16554473 | 0.84 | — | — | |
| SCHEMBL16565821 | 0.83 | CYP11B2 (0.31) | CYP11B2 | |
| SCHEMBL7694965 | 0.81 | CYP11B1 (0.35) | BACE1CYP11B2CYP11B1USP14 | |
| SCHEMBL16565894 | 0.78 | — | — | |
| SCHEMBL17940883 | 0.78 | — | — | |
| SCHEMBL17940936 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160214974-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-07-28 | — | — | US | disclosed |
| EP-3041833-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015032617-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214974-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP1B1, CHRM1 | BACE1 1284/4885CYP11B2 2471/4885CYP11B1 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.