Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554409 | 0.92 | ALDH1A1 (0.56) | GAAALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL16554529 | 0.92 | PTGS2 (0.47) | GAAALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL16554971 | 0.91 | PTGS2 (0.55) | GAAALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL16554932 | 0.91 | ALDH1A1 (0.48) | GAAALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL16554719 | 0.91 | PTGS2 (0.53) | GAAALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL16554496 | 0.90 | MAPT (0.52) | GAAALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL16554359 | 0.89 | ALDH1A1 (0.49) | GAAALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL16554439 | 0.88 | MEN1 (0.42) | GAAALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL16554515 | 0.88 | RAB9A (0.54) | ALDH1A1LMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL16554507 | 0.88 | KCNQ3 (0.43) | GAAALDH1A1SMN1; SMN2NQO2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | claimed |
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | disclosed |