Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 7/20 | 0.60 |
| ▸ | MET | P08581 | 13/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.46 |
| ▸ | AXL | P30530 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | MST1R | Q04912 | 3/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.43 |
| ▸ | LTK | P29376 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | YES1 | P07947 | 1/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL489020 | 0.82 | INPPL1 (0.88) | INPPL1MET | |
| SCHEMBL16555031 | 0.78 | INPPL1 (0.48) | INPPL1METKDRSRCFGFR2 | |
| SCHEMBL488367 | 0.78 | MET (0.68) | INPPL1MET | |
| SCHEMBL30453362 | 0.78 | MET (0.68) | INPPL1MET | |
| SCHEMBL30452797 | 0.74 | MET (0.57) | MET | |
| SCHEMBL488243 | 0.74 | MET (0.57) | MET | |
| SCHEMBL1000603 | 0.73 | NOS3 (0.46) | — | |
| 2-Aminopyridine SCHEMBL27650128 | 0.73 | MET (0.51) | INPPL1METKDRSRCFGFR2 | |
| SCHEMBL488072 | 0.73 | MET (0.59) | MET | |
| SCHEMBL30453574 | 0.73 | MET (0.59) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015034729-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-03-12 | — | — | WO | disclosed |