Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 5/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | TPO | P07202 | 1/20 | 0.44 |
| ▸ | EPX | P11678 | 1/20 | 0.44 |
| ▸ | LPO | P22079 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 5/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 6/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MST1R | Q04912 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ETV6 | P41212 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16555527 | 0.78 | INPPL1 (0.60) | INPPL1METKDRSRCKIT | |
| SCHEMBL1000603 | 0.76 | NOS3 (0.46) | MPOTPOEPXLPOLTA4H | |
| SCHEMBL13577142 | 0.75 | MET (0.42) | INPPL1METKDRSRCKIT | |
| SCHEMBL3102747 | 0.75 | NR4A1 (0.41) | INPPL1METKDRSRCKIT | |
| Hydrochloric Acid SCHEMBL710140 | 0.75 | NOS3 (0.45) | MPOTPOEPXLPOLTA4H | |
| SCHEMBL13577182 | 0.73 | CYP3A4 (0.47) | INPPL1METKDRSRCKIT | |
| SCHEMBL13577014 | 0.72 | MET (0.48) | INPPL1METKDRSRCKIT | |
| SCHEMBL15779489 | 0.70 | MET (0.71) | LTA4HMETJAK2 | |
| SCHEMBL488890 | 0.70 | MET (0.44) | METJAK2 | |
| SCHEMBL13075015 | 0.69 | MCHR1 (0.45) | MPOTPOEPXLPOLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015034729-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-03-12 | — | — | WO | disclosed |