Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469986 | 0.79 | CYP3A4 (0.30) | — | |
| SCHEMBL11461855 | 0.78 | — | — | |
| SCHEMBL2489442 | 0.74 | ALDH1A1 (0.44) | KDM4ENPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL12332804 | 0.72 | KDM4E (0.31) | KDM4ENPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL10486890 | 0.71 | CYP3A4 (0.32) | — | |
| SCHEMBL14739957 | 0.66 | KDM1A (0.31) | KDM4E | |
| SCHEMBL8628094 | 0.61 | — | — | |
| SCHEMBL11846055 | 0.61 | — | — | |
| SCHEMBL10712331 | 0.61 | ALDH1A1 (0.70) | KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL2593177 | 0.60 | APAF1 (0.45) | KDM4ENPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | disclosed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | CYP51A1, TALDO1, IL33 | KDM4E 4127/4885NPSR1 3899/4885CRHR1 3292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.