Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054902 | 0.83 | ADH1B (0.42) | GSRFOLH1ADH1BADH1CADH1A | |
| SCHEMBL17210488 | 0.82 | GSR (0.42) | GSRFOLH1ADH1BADH1CADH1A | |
| SCHEMBL23615392 | 0.82 | CPB2 (0.36) | GSRFOLH1ADH1BADH1CADH1A | |
| SCHEMBL13218612 | 0.80 | GSR (0.44) | GSRFOLH1ADH1BADH1CADH1A | |
| SCHEMBL20435279 | 0.80 | FOLH1 (0.41) | GSRFOLH1GNAI3GNAO1GNAI1 | |
| SCHEMBL1168516 | 0.80 | GSR (0.53) | GSRFOLH1SLC6A5RNPEPCPB2 | |
| SCHEMBL1168511 | 0.80 | GSR (0.53) | GSRFOLH1SLC6A5RNPEPCPB2 | |
| SCHEMBL18105654 | 0.80 | GSR (0.44) | GSRFOLH1ADH1BADH1CADH1A | |
| SCHEMBL28786641 | 0.80 | GSR (0.53) | GSRFOLH1SLC6A5RNPEPCPB2 | |
| SCHEMBL27250381 | 0.80 | FOLH1 (0.41) | GSRFOLH1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015035102-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2015-03-12 | — | — | WO | disclosed |