Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628861 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CUL4A | |
| SCHEMBL1398115 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10ADORA2A | |
| SCHEMBL186269 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10CUL4A | |
| SCHEMBL29267462 | 0.82 | KMT2A (0.39) | ALDH1A1KDM4EHPGDHSD17B10CUL4A | |
| Cyanide SCHEMBL28871133 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10CUL4A | |
| SCHEMBL27606196 | 0.78 | LRRK2 (0.34) | ALDH1A1KDM4EHPGDHSD17B10CUL4A | |
| SCHEMBL17086513 | 0.77 | CYP3A4 (0.35) | ALDH1A1HPGDHSD17B10CUL4ACYP3A4 | |
| SCHEMBL6151711 | 0.77 | CYP3A4 (0.35) | ALDH1A1HPGDHSD17B10CUL4ACYP3A4 | |
| SCHEMBL2432926 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CUL4A | |
| SCHEMBL19062287 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CUL4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 725 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223261-A1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | FIRMENICH SA (CH) | 2025-07-10 | — | — | US | claimed |
| EP-4472950-B1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | FIRMENICH & CIE (CH) | 2025-06-25 | — | — | EP | claimed |
| CN-119528741-A | Preparation method of rituximab key intermediate | 济南鼎皓医药科技有限公司 | 2025-02-28 | — | — | CN | claimed |
| EP-4472950-A1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | Firmenich SA (CH) | 2024-12-11 | — | — | EP | claimed |
| CN-118459454-B | Preparation method of sweet taste regulator | 济南悟通生物科技有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-118459454-A | Preparation method of sweet taste regulator | 济南悟通生物科技有限公司 | 2024-08-09 | — | — | CN | claimed |
| WO-2023209143-A1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | FIRMENICH SA (CH) | 2023-11-02 | — | — | WO | claimed |
| CN-111548276-B | Preparation method of 2,6-dibromoaniline | 宁夏大学 | 2022-12-16 | — | — | CN | claimed |
| CN-111548276-A | Preparation method of 2, 6-dibromoaniline | 宁夏大学 | 2020-08-18 | — | — | CN | claimed |
| CN-108610293-B | Method for preparing dorvitinib intermediate by adopting microchannel reaction device | 南京工业大学 | 2020-08-04 | — | — | CN | claimed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | claimed |
| EP-1648874-A2 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-04-26 | — | — | EP | claimed |
| US-20050065143-A1 | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2005-03-24 | — | — | US | claimed |
| WO-2005011655-A2 | PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2005-02-10 | — | — | WO | claimed |
| EP-1422218-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-26 | — | — | EP | claimed |
| CN-1049498-A | 2,4-diamino-5-replacement-6-(N-replaces benzyl amino) quinazoline derivant is synthetic | SHANGHAI INST PHARM INDUSTRY (CN) | 1991-02-27 | — | — | CN | claimed |
| US-4504660-A | Process for the production of 2,6-diaminobenzonitrile derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-03-12 | — | — | US | claimed |
| EP-0053247-B1 | PROCESS FOR PREPARATION OF 6-FLUORO-ANTHRANILIC ACID NITRILE OR 6-FLUORO-ANTHRANILIC ACID AND 6-FLUORO-ANTHRANILIC ACID NITRILE | BASF Aktiengesellschaft (DE) | 1984-01-18 | — | — | EP | claimed |
| US-4359428-A | Preparation of fluorinated anthranilic acid and anthranilonitrile | BASF AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | claimed |
| EP-0053247-A1 | Process for preparation of 6-fluoro-anthranilic acid nitrile or 6-fluoro-anthranilic acid and 6-fluoro-anthranilic acid nitrile | BASF Aktiengesellschaft (DE) | 1982-06-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065143-A1 | Pyridazine derivatives and their use as therapeutic agents | PRDX5, SNRPD3, SNRPD2 | ALDH1A1 2432/4885KDM4E 1401/4885HPGD 1795/4885 |
| US-20250223261-A1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | TAS2R4, TAS2R50, TAS2R60 | ALDH1A1 412/4885KDM4E 936/4885HPGD 2492/4885 |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | PTGS2, PTGES2, PTGES | ALDH1A1 483/4885KDM4E 1317/4885HPGD 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.