Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | UQCRB | P14927 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL16563276 | 0.85 | KIF11 (0.43) | ALDH1A1LMNACA1CA2MAPT | |
| SCHEMBL196750 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNAGAACA1CA2 | |
| Ammonia Solution, Strong SCHEMBL27721989 | 0.82 | ALDH1A1 (0.59) | ALDH1A1LMNAGAACA1CA2 | |
| Hydrochloric Acid SCHEMBL1326865 | 0.82 | ALDH1A1 (0.59) | ALDH1A1LMNAGAACA1CA2 | |
| Lithium Ion SCHEMBL16563178 | 0.81 | SNCA (0.46) | ALDH1A1LMNAGAACA1CA2 | |
| Lithium Ion SCHEMBL16563239 | 0.79 | LMNA (0.43) | ALDH1A1LMNACA1CA2MEN1 | |
| SCHEMBL16563244 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNAGAACA1CA2 | |
| Lithium Ion SCHEMBL16563074 | 0.79 | TSHR (0.61) | ALDH1A1LMNACA1CA2POLB | |
| SCHEMBL16563158 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAGAACA1CA2 | |
| SCHEMBL25384264 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9595737-B2 | Non-aqueous electrolyte and power storage device using same | UBE INDUSTRIES, LTD. (JP) | 2017-03-14 | — | — | US | disclosed |
| EP-2849272-B1 | NON-AQUEOUS ELECTROLYTE AND POWER STORAGE DEVICE USING SAME | UBE INDUSTRIES (JP) | 2017-01-11 | — | — | EP | disclosed |
| US-20150125761-A1 | NON-AQUEOUS ELECTROLYTE AND POWER STORAGE DEVICE USING SAME | UBE INDUSTRIES, LTD. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2849272-A1 | NON-AQUEOUS ELECTROLYTE AND POWER STORAGE DEVICE USING SAME | UBE Industries, Ltd. (JP) | 2015-03-18 | — | — | EP | disclosed |