SCHEMBL5964558

SCHEMBL5964558

CCN(CC)c1ccc2c(C=O)cc(=O)oc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.72
IGLV6-57 P01721 6/20 0.72
L3MBTL1 Q9Y468 6/20 0.72
HPGD P15428 5/20 0.72
GLA P06280 5/20 0.72
ATM Q13315 4/20 0.72
CYP3A4 P08684 3/20 0.72
CASP1 P29466 3/20 0.72
CASP7 P55210 3/20 0.72
HSD17B10 Q99714 3/20 0.72
MAPK1 P28482 2/20 0.72
HIF1A Q16665 2/20 0.72
KDM4E B2RXH2 7/20 0.66
MEN1 O00255 5/20 0.66
KMT2A Q03164 5/20 0.66
MAPT P10636 5/20 0.66
TDP1 Q9NUW8 4/20 0.66
CYP1A2 P05177 2/20 0.66
CYP2C9 P11712 2/20 0.66
CYP2C19 P33261 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22265905 0.89 ALDH1A1 (0.68) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL16563262 0.84 IGLV6-57 (0.54) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL3363203 0.84 ALDH1A1 (0.61) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL22927922 0.84 ALDH1A1 (0.61) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL29362472 0.84 ALDH1A1 (1.00) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL67108 0.84 ALDH1A1 (1.00) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL384286 0.84 ALDH1A1 (1.00) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL1395286 0.84 IGLV6-57 (0.51) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL6690441 0.81 ALDH1A1 (0.73) ALDH1A1IGLV6-57L3MBTL1HPGDGLA
SCHEMBL5964617 0.79 ALDH1A1 (0.71) ALDH1A1IGLV6-57L3MBTL1HPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116898792-A Medicine carrying micro robot and preparation method and use method thereof 广东工业大学 2023-10-20 CN claimed
CN-108456188-B 7-diethylamino-4-hydroxymethyl coumarin derivative, preparation method and application thereof as nano fragrance precursor 华东理工大学 2021-09-24 CN claimed
EP-3860654-B1 PHOTORESPONSIVE NUTLIN DERIVATIVES AND USES THEREOF UNIV GRONINGEN (NL) 2025-06-25 EP disclosed
US-20250011768-A1 Stabilized CRISPR Complexes SYNTHEGO CORPORATION 2025-01-09 US disclosed
US-12139707-B2 Stabilized CRISPR complexes SYNTHEGO CORPORATION (US) 2024-11-12 US disclosed
WO-2024206514-A1 COUMARIN PHOTOBASE GENERATORS FOR POLYIMIDE FORMATION NITTO DENKO CORPORATION (JP) 2024-10-03 WO disclosed
US-20240209356-A1 Systems and Methods for Modulating CRISPR Activity SYNTHEGO CORPORATION 2024-06-27 US disclosed
US-20240209356-A1 Systems and Methods for Modulating CRISPR Activity SYNTHEGO CORPORATION 2024-06-27 US disclosed
US-20240209356-A1 Systems and Methods for Modulating CRISPR Activity SYNTHEGO CORPORATION 2024-06-27 US disclosed
US-11981664-B2 Photoresponsive nutlin derivatives and uses thereof RIJKSUNIVERSITEIT GRONINGEN (NL) 2024-05-14 US disclosed
US-11884918-B2 Systems and methods for modulating CRISPR activity SYNTHEGO CORPORATION (US) 2024-01-30 US disclosed
WO-2021016135-A1 STABILIZED CRISPR COMPLEXES SYNTHEGO CORPORATION (US) 2021-01-28 WO disclosed
WO-2021016135-A1 STABILIZED CRISPR COMPLEXES SYNTHEGO CORPORATION (US) 2021-01-28 WO disclosed
CN-111919843-A Photoresponsive chitosan-based nano pesticide and preparation method thereof 贵州大学 2020-11-13 CN disclosed
WO-2020154714-A2 SYSTEMS AND METHODS FOR MODULATING CRISPR ACTIVITY SYNTHEGO CORPORATION (US) 2020-07-30 WO disclosed
WO-2020071911-A1 PHOTORESPONSIVE NUTLIN DERIVATIVES AND USES THEREOF RIJKSUNIVERSITEIT GRONINGEN (NL) 2020-04-09 WO disclosed
WO-2020071911-A1 PHOTORESPONSIVE NUTLIN DERIVATIVES AND USES THEREOF RIJKSUNIVERSITEIT GRONINGEN (NL) 2020-04-09 WO disclosed
US-20100324266-A1 Photocleavable Protecting Groups AFFYMETRIX, INC. (US) 2010-12-23 US disclosed
US-20090076295-A1 PHOTOCLEAVABLE PROTECTING GROUPS AFFYMETRIX, INC. (US) 2009-03-19 US disclosed
US-20060008907-A1 Control of gene expression via light activated RNA interference THE CURATORS OF THE UNIVERSITY OF MISSOURI 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981664-B2 Photoresponsive nutlin derivatives and uses thereof NUTF2, DNER, TP53 ALDH1A1 2891/4885IGLV6-57 3493/4885L3MBTL1 4816/4885
US-12139707-B2 Stabilized CRISPR complexes DCLRE1B, CPSF1, MRE11 ALDH1A1 4832/4885IGLV6-57 2490/4885L3MBTL1 303/4885
US-20100324266-A1 Photocleavable Protecting Groups POLL, PCNA, ERCC4 ALDH1A1 1340/4885IGLV6-57 964/4885L3MBTL1 399/4885
US-20090076295-A1 PHOTOCLEAVABLE PROTECTING GROUPS POLL, PCNA, ERCC4 ALDH1A1 1340/4885IGLV6-57 964/4885L3MBTL1 399/4885
US-20250011768-A1 Stabilized CRISPR Complexes DCLRE1B, CPSF1, MRE11 ALDH1A1 4832/4885IGLV6-57 2490/4885L3MBTL1 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.