Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16568994 | 0.78 | L3MBTL1 (0.53) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL1305530 | 0.74 | PPARA (0.55) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL31296401 | 0.74 | PPARA (0.47) | KMT2AMEN1LMNAMAPTCYP3A4 | |
| SCHEMBL1304683 | 0.73 | PPARA (0.61) | KMT2AMEN1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL1305271 | 0.72 | CA1 (0.58) | KMT2AMEN1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL12099902 | 0.72 | DHODH (0.56) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL1304404 | 0.71 | MEN1 (0.49) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL11007336 | 0.70 | KMT2A (0.70) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL6544670 | 0.70 | L3MBTL1 (0.67) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL9561356 | 0.70 | MAPT (0.67) | KMT2AMEN1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170332910-A1 | MODIFIED PARAMAGNETIC NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTICS AND METHODS THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-11-23 | — | — | US | disclosed |
| US-20160346389-A1 | MODIFIED PARAMAGNETIC NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTICS AND METHODS THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2016-12-01 | — | — | US | disclosed |
| WO-2016073348-A1 | MODIFIED PARAMAGNETIC NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTICS AND METHODS THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
| WO-2015038924-A1 | MODIFIED PARAMAGNETIC NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTICS AND METHODS THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-03-19 | — | — | WO | disclosed |