Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12099902 | 0.89 | DHODH (0.56) | L3MBTL1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6544670 | 0.89 | L3MBTL1 (0.67) | L3MBTL1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1305530 | 0.80 | PPARA (0.55) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL16568997 | 0.78 | KMT2A (0.44) | L3MBTL1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9561356 | 0.78 | MAPT (0.67) | L3MBTL1MEN1KMT2AMAPTLMNA | |
| SCHEMBL5309687 | 0.76 | ALDH1A1 (0.54) | L3MBTL1KMT2AMAPTLMNAHTT | |
| SCHEMBL11007336 | 0.73 | KMT2A (0.70) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL14975400 | 0.73 | NPC1 (0.61) | L3MBTL1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1305899 | 0.73 | MEN1 (0.63) | L3MBTL1MEN1KMT2AMAPTLMNA | |
| SCHEMBL12017475 | 0.72 | KDM4E (0.57) | L3MBTL1MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170332910-A1 | MODIFIED PARAMAGNETIC NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTICS AND METHODS THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-11-23 | — | — | US | disclosed |
| US-20160346389-A1 | MODIFIED PARAMAGNETIC NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTICS AND METHODS THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2016-12-01 | — | — | US | disclosed |
| WO-2016073348-A1 | MODIFIED PARAMAGNETIC NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTICS AND METHODS THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
| WO-2015038924-A1 | MODIFIED PARAMAGNETIC NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTICS AND METHODS THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-03-19 | — | — | WO | disclosed |