Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147358 | 0.85 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL6301912 | 0.84 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL14633632 | 0.84 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL27499998 | 0.83 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL642700 | 0.82 | KMT2A (0.81) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7776355 | 0.82 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL16922176 | 0.82 | KMT2A (0.81) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL6815786 | 0.82 | MAPT (0.76) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL4050791 | 0.81 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| Phosphine SCHEMBL28320532 | 0.81 | KMT2A (0.78) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| US-9687832-B2 | Bifunctional organic catalysts | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-06-27 | — | — | US | disclosed |
| US-20150298109-A1 | BIFUNCTIONAL ORGANIC CATALYSTS | ISIS INNOVATION LIMITED (GB) | 2015-10-22 | — | — | US | disclosed |
| EP-2444085-B1 | Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer | UNIV CALIFORNIA (US) | 2015-03-18 | — | — | EP | disclosed |
| CN-102171190-A | Insecticidal benzenedicarboxamide derivative | BAYER CROPSCIENCE AG | 2011-08-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150298109-A1 | BIFUNCTIONAL ORGANIC CATALYSTS | CCNL2, UBE2L3, ARL1 | ALDH1A1 1163/4885SMN1; SMN2 3813/4885KMT2A 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.