SCHEMBL7776355

SCHEMBL7776355

O=[N+]([O-])c1ccc(NC(O)=S)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.66
SMN1; SMN2 Q16637 5/20 0.66
MEN1 O00255 7/20 0.66
KMT2A Q03164 7/20 0.66
MAPT P10636 5/20 0.61
LMNA P02545 5/20 0.61
HTT P42858 4/20 0.61
GAA P10253 4/20 0.61
NPC1 O15118 3/20 0.61
ALOX12 P18054 3/20 0.61
TDP1 Q9NUW8 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
RAB9A P51151 2/20 0.59
MITF O75030 1/20 0.59
POLB P06746 1/20 0.59
TGM2 P21980 1/20 0.56
HPGD P15428 2/20 0.55
PKM P14618 1/20 0.55
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14633632 0.86 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL6301912 0.86 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL5078630 0.83 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL6310259 0.82 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL16573282 0.82 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL147358 0.82 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL152811 0.82 KMT2A (0.74) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL10974048 0.81 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL27499998 0.81 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL6297678 0.81 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9077741-A None JP disclosed
EP-0832757-B1 REVERSIBLE THERMAL RECORDING MEDIUM OJI PAPER CO (JP) 2001-08-22 EP disclosed
US-5928988-A CONTAINING SULFONYLUREA COLOR DEVELOPER OJI PAPER CO., LTD. (JP) 1999-07-27 US disclosed
EP-0832757-A1 REVERSIBLE THERMAL RECORDING MEDIUM Oji Paper Co., Ltd. (JP) 1998-04-01 EP disclosed
JP-H0977741-A TOLUENESULFONYLUREA-BASED COMPOUND AND DEVELOPER FOR REVERSIBLE HEAT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME OJI PAPER CO LTD 1997-03-25 JP disclosed