SCHEMBL16574232

SCHEMBL16574232

CCCOCCOCCOC1CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16569832 1.00 KDM4E (0.33) KDM4EALDH1A1
SCHEMBL4742224 0.89 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL4743396 0.82 PPP5C (0.36) KDM4EALDH1A1
SCHEMBL12228730 0.81 GBA1 (0.39) KDM4EALDH1A1
SCHEMBL4783622 0.79 GBA1 (0.42) KDM4EALDH1A1
SCHEMBL12228729 0.79 GBA1 (0.42) KDM4EALDH1A1
SCHEMBL1615141 0.77 ALDH1A1 (0.38) KDM4EALDH1A1
SCHEMBL16574230 0.76 KDM4E (0.42) KDM4EALDH1A1
SCHEMBL6393373 0.75 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL15611269 0.74 MGLL (0.34) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180203349-A1 PHOTOIMAGEABLE POLYOLEFIN COMPOSITIONS CONTAINING PHOTOBASE GENERATORS PROMERUS, LLC (US) 2018-07-19 US disclosed
US-9952507-B2 Photoimageable polyolefin compositions containing photobase generators PROMERUS, LLC (US) 2018-04-24 US disclosed
US-9938241-B2 Diazirine compounds and compositions derived therefrom PROMERUS, LLC (US) 2018-04-10 US disclosed
US-9834627-B2 Polymers derived from norbornadiene and maleic anhydride and use thereof PROMERUS, LLC (US) 2017-12-05 US disclosed
US-9823565-B2 Photoimageable compositions containing photobase generators PROMERUS, LLC (US) 2017-11-21 US disclosed
US-9765168-B2 Flame retardant vinyl addition polycycloolefinic polymers PROMERUS, LLC (US) 2017-09-19 US disclosed
US-20170190810-A1 POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF PROMERUS, LLC (US) 2017-07-06 US disclosed
US-9690196-B2 Photoimageable compositions containing thermal base generators PROMERUS, LLC (US) 2017-06-27 US disclosed
US-9610549-B2 Polycyclo-olefinic block copolymers PROMERUS, LLC (US) 2017-04-04 US disclosed
US-9575409-B2 Photoimageable compositions containing oxetane functionality PROMERUS, LLC (US) 2017-02-21 US disclosed
US-20160238931-A1 PHOTOIMAGEABLE COMPOSITIONS CONTAINING PHOTOBASE GENERATORS SUMITOMO BAKELITE CO., LTD. (JP) 2016-08-18 US disclosed
US-20160238932-A1 PHOTOIMAGEABLE POLYOLEFIN COMPOSITIONS CONTAINING PHOTOBASE GENERATORS SUMITOMO BAKELITE CO., LTD. (JP) 2016-08-18 US disclosed
US-20160187775-A1 PHOTOIMAGEABLE COMPOSITIONS CONTAINING THERMAL BASE GENERATORS SUMITOMO BAKELITE CO., LTD. (JP) 2016-06-30 US disclosed
US-20160147145-A1 PHOTOIMAGEABLE COMPOSITIONS CONTAINING OXETANE FUNCTIONALITY PROMERUS, LLC 2016-05-26 US disclosed
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM SUMITOMO BAKELITE CO., LTD. (JP) 2016-03-24 US disclosed
US-9291901-B2 Amine treated maleic anhydride polymers with pendent silyl group, compositions and applications thereof SUMITOMO BAKELITE CO., LTD. (JP) 2016-03-22 US disclosed
US-20160051945-A1 PERVAPORATION MEMBRANES DERIVED FROM POLYCYCLO-OLEFINIC BLOCK COPOLYMERS SUMITOMO BAKELITE CO., LTD. (JP) 2016-02-25 US disclosed
US-20160046752-A1 POLYCYCLO-OLEFINIC BLOCK COPOLYMERS SUMITOMO BAKELITE CO., LTD. (JP) 2016-02-18 US disclosed
US-20150079507-A1 AMINE TREATED MALEIC ANHYDRIDE POLYMERS WITH PENDENT SILYL GROUP, COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2015-03-19 US disclosed
US-20150079506-A1 AMINE TREATED MALEIC ANHYDRIDE POLYMERS, COMPOSITIONS AND APPLICATIONS THEREOF SUMITOMO BAKELITE CO., LTD (JP) 2015-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM RDX, AOX1, ALDH1A2 KDM4E 2719/4885ALDH1A1 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.