Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525187 | 0.94 | POLB (0.57) | TSHRCES1MEN1KMT2APOLB | |
| SCHEMBL27815181 | 0.83 | MAPT (0.67) | TSHRCES1MEN1KMT2APOLB | |
| SCHEMBL28723007 | 0.83 | MEN1 (0.82) | TSHRCES1MEN1KMT2APOLB | |
| SCHEMBL28446043 | 0.83 | MAPT (0.57) | TSHRCES1MEN1KMT2APOLB | |
| SCHEMBL28246965 | 0.83 | CTSD (0.54) | TSHRCES1MEN1KMT2APOLB | |
| SCHEMBL30378267 | 0.83 | TSHR (0.47) | TSHRCES1MEN1KMT2APOLB | |
| SCHEMBL11621538 | 0.82 | MAPT (0.81) | CES1MEN1KMT2APOLBMAPT | |
| SCHEMBL14277712 | 0.82 | MPO (0.53) | TSHRMEN1KMT2APOLBCA1 | |
| SCHEMBL296991 | 0.82 | MEN1 (0.68) | TSHRCES1MEN1KMT2APOLB | |
| SCHEMBL9592831 | 0.81 | TSHR (0.63) | TSHRCES1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-119977832-A | Benzoyl hydrazine antineoplastic compound and preparation method and application thereof | 江苏海洋大学 | 2025-05-13 | — | — | CN | claimed |
| WO-2025090061-A1 | ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION | JP LABORATORIES, INC. (US) | 2025-05-01 | — | — | WO | claimed |
| WO-2025075611-A1 | ULTRASONIC INDICATOR BASED ON EMULSION FORMATION | JP LABORATORIES, INC. (US) | 2025-04-10 | — | — | WO | claimed |
| CN-118812539-A | 5-Aminotriazolopyrimidine derivative and preparation method thereof | 苏州大学 | 2024-10-22 | — | — | CN | claimed |
| CN-114057628-B | Pyridine quaternary ammonium salt anion recognition receptor and preparation method and application thereof | 河西学院 | 2023-04-18 | — | — | CN | claimed |
| US-11398630-B2 | Method of generating energy from a hydrazide containing anode fuel, and fuel cell | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-07-26 | — | — | US | claimed |
| CN-114057628-A | Pyridine quaternary ammonium salt anion recognition receptor and preparation method and application thereof | 河西学院 | 2022-02-18 | — | — | CN | claimed |
| CN-112592339-A | 1,3, 4-oxadiazole-2 (3H) -thione-norfloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-04-02 | — | — | CN | claimed |
| US-20210005900-A1 | METHOD OF GENERATING ENERGY FROM A HYDRAZIDE CONTAINING ANODE FUEL, AND FUEL CELL | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2021-01-07 | — | — | US | claimed |
| US-20030105140-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-06-05 | — | — | US | claimed |
| WO-2002102301-A2 | SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-12-27 | — | — | WO | claimed |
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2002-09-12 | — | — | US | claimed |
| WO-2002051846-A1 | APICIDIN-DERIVATIVES, THEIR SYNTHETIC METHODS, AND ANTITUMOR COMPOSITIONS CONTAINING THE SAME | ZEE, OK PYO (KR) | 2002-07-04 | — | — | WO | claimed |
| EP-0581904-B1 | METHOD OF INHIBITING FIBROSIS | UNIV DUKE (US) | 1997-05-28 | — | — | EP | claimed |
| US-5571846-A | Method of inhibiting fibrosis | DUKE UNIVERSITY (US) | 1996-11-05 | — | — | US | claimed |
| US-5527385-A | CONTAINING ELECTRON DONATING CHROMOGENIC COMPOUND, ELECTRON ACCEPTING COMPOUND, HYDRAZIDE COMPOUND DESENSITIZER, TRANSITION TEMPERATURE MODIFIER | SAKURA COLOR PRODUCTS CORPORATION (JP) | 1996-06-18 | — | — | US | claimed |
| EP-0581904-A4 | METHOD OF INHIBITING FIBROSIS | UNIV DUKE (US) | 1994-05-25 | — | — | EP | claimed |
| EP-0581904-A1 | METHOD OF INHIBITING FIBROSIS. | UNIV DUKE (US) | 1994-02-09 | — | — | EP | claimed |
| WO-1992017065-A2 | METHOD OF INHIBITING FIBROSIS | DUKE UNIVERSITY (US) | 1992-10-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | TSHR 2028/4885CES1 2554/4885MEN1 2427/4885 |
| US-20030105140-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | TSHR 2028/4885CES1 2554/4885MEN1 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.