SCHEMBL16577196

SCHEMBL16577196

CC(C)(C)O[C@H]1OC(CO)[C@@H](O)[C@H](O)C1N

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ MAPT P10636 1/20 0.50
▸ LMNA P02545 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ TSHR P16473 2/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ MEN1 O00255 2/20 0.40
▸ LRAT O95237 1/20 0.40
▸ TRPV1 Q8NER1 1/20 0.40
▸ POLB P06746 1/20 0.39
▸ GJA1 P17302 1/20 0.39
▸ GJB2 P29033 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20713592 1.00 L3MBTL1 (0.51) L3MBTL1MAPTLMNAKDM4EALOX15
SCHEMBL20713636 1.00 L3MBTL1 (0.51) L3MBTL1MAPTLMNAKDM4EALOX15
SCHEMBL22639646 1.00 L3MBTL1 (0.51) L3MBTL1MAPTLMNAKDM4EALOX15
SCHEMBL16688093 1.00 L3MBTL1 (0.51) L3MBTL1MAPTLMNAKDM4EALOX15
SCHEMBL16577216 1.00 L3MBTL1 (0.51) L3MBTL1MAPTLMNAKDM4EALOX15
SCHEMBL16589049 1.00 L3MBTL1 (0.51) L3MBTL1MAPTLMNAKDM4EALOX15
SCHEMBL23743113 0.91 L3MBTL1 (0.44) L3MBTL1MAPTLMNAKDM4EALOX15
SCHEMBL22429030 0.87 L3MBTL1 (0.42) L3MBTL1MAPTLMNAKDM4EALOX15
SCHEMBL15459182 0.86 LRAT (0.50) LMNAKDM4EALOX15TSHRHSD17B10
SCHEMBL15459179 0.86 L3MBTL1 (0.51) L3MBTL1MAPTLMNAKDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067672-A1 FLAVONE DERIVATIVE FOR TREATING TUMORS AND USE THEREOF SICHUAN FUSHENGYUAN TECHNOLOGY CO., LTD (CN) 2024-02-29 — — US disclosed
US-9403857-B2 Compositions and methods for the treatment of metabolic syndrome CELLIX BIO PRIVATE LIMITED (IN) 2016-08-02 — — US disclosed
US-9321716-B1 Compositions and methods for the treatment of metabolic syndrome CELLIX BIO PRIVATE LIMITED (IN) 2016-04-26 — — US disclosed
US-9315478-B2 Compositions and methods for the treatment of metabolic syndrome CELLIX BIO PRIVATE LIMITED (IN) 2016-04-19 — — US disclosed
US-20150126497-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC SYNDROME CELLIX BIO PRIVATE LIMITED (IN) 2015-05-07 — — US disclosed
US-20150087660-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CHRONIC DISEASES AND INFLAMMATORY DISORDERS KANDULA MAHESH (IN) 2015-03-26 — — US disclosed
US-20150080345-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC SYNDROME CELLIX BIO PRIVATE LIMITED (IN) 2015-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067672-A1 FLAVONE DERIVATIVE FOR TREATING TUMORS AND USE THEREOF TPD52L2, F12, H1-0 L3MBTL1 216/4885MAPT 4763/4885LMNA 2178/4885
US-20150080345-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC SYNDROME FABP4, GYS2, FABP2 L3MBTL1 3881/4885MAPT 830/4885LMNA 2634/4885
US-20150087660-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CHRONIC DISEASES AND INFLAMMATORY DISORDERS IL1B, IAPP, CXCL12 L3MBTL1 3809/4885MAPT 852/4885LMNA 1389/4885
US-20150126497-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC SYNDROME SLC5A1, IRS1, SLC5A2 L3MBTL1 1780/4885MAPT 1018/4885LMNA 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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