Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596397 | 0.92 | ELANE (0.38) | KMT2AMEN1THRBELANERAB9A | |
| SCHEMBL16561456 | 0.90 | ELANE (0.53) | KMT2AMEN1ELANERAB9ALMNA | |
| SCHEMBL16445450 | 0.90 | LMNA (0.53) | KMT2AMEN1THRBLMNAMAPT | |
| SCHEMBL1888207 | 0.90 | ALDH1A1 (0.42) | KMT2AMEN1THRBELANERAB9A | |
| SCHEMBL16561448 | 0.90 | CES1 (0.45) | KMT2AMEN1THRBELANEMAPT | |
| SCHEMBL165891 | 0.89 | TDP1 (0.42) | KMT2ATHRBELANEMAPTHSD17B10 | |
| SCHEMBL8822688 | 0.87 | THRB (0.47) | KMT2AMEN1THRBELANESMN1; SMN2 | |
| SCHEMBL14984746 | 0.87 | THRB (0.47) | KMT2AMEN1THRBELANERAB9A | |
| SCHEMBL3793128 | 0.87 | MAPT (0.52) | KMT2AMEN1ELANERAB9ALMNA | |
| SCHEMBL14984466 | 0.87 | THRB (0.47) | KMT2AMEN1THRBELANERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150086914-A1 | IMAGING MEMBERS AND METHODS FOR MAKING THE SAME | XEROX CORPORATION (US) | 2015-03-26 | — | — | US | claimed |
| US-9075327-B2 | Imaging members and methods for making the same | XEROX CORPORATION (US) | 2015-07-07 | — | — | US | disclosed |
| US-9017907-B2 | Flexible imaging members having externally plasticized imaging layer(s) | XEROX CORPORATION (US) | 2015-04-28 | — | — | US | disclosed |
| US-20150086914-A1 | IMAGING MEMBERS AND METHODS FOR MAKING THE SAME | XEROX CORPORATION (US) | 2015-03-26 | — | — | US | disclosed |