SCHEMBL16596397

SCHEMBL16596397

C=COC(=O)Oc1ccc(OC(=O)O)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 2/20 0.36
THRB P10828 2/20 0.36
HSD17B10 Q99714 1/20 0.35
MAPT P10636 3/20 0.34
ALDH1A1 P00352 1/20 0.34
HSP90AA1 P07900 1/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TTR P02766 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16583199 0.92 KMT2A (0.42) ELANEMEN1KMT2ALMNATHRB
SCHEMBL16561456 0.86 ELANE (0.53) ELANEMEN1KMT2ALMNAMAPT
SCHEMBL165891 0.86 TDP1 (0.42) ELANEKMT2ATHRBHSD17B10MAPT
SCHEMBL3788871 0.84 ELANE (0.59) ELANEMEN1KMT2AALDH1A1GAA
SCHEMBL16445450 0.82 LMNA (0.53) MEN1KMT2ALMNATHRBMAPT
SCHEMBL16561448 0.82 CES1 (0.45) ELANEMEN1KMT2ATHRBMAPT
SCHEMBL1888207 0.82 ALDH1A1 (0.42) ELANEMEN1KMT2ALMNATHRB
Acetic Acid SCHEMBL27510047 0.81 ALDH1A1 (0.45) ELANEMEN1KMT2ATHRBHSD17B10
SCHEMBL3795351 0.80 CES2 (0.51) ELANEMEN1KMT2A
SCHEMBL28169967 0.80 TDP1 (0.41) ELANEMEN1KMT2ATHRBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 US disclosed
US-9017907-B2 Flexible imaging members having externally plasticized imaging layer(s) XEROX CORPORATION (US) 2015-04-28 US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 US disclosed