SCHEMBL165867

SCHEMBL165867

N#Cc1ccc(N)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
EGLN2 Q96KS0 5/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
KIF11 P52732 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HDAC1 Q13547 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29726483 1.00 ALDH1A1 (0.50) ALDH1A1EGLN2KDM4EGAACA12
Hydrochloric Acid SCHEMBL29261706 0.98 ALDH1A1 (0.48) ALDH1A1EGLN2KDM4EGAACA12
Methane SCHEMBL27670217 0.98 ALDH1A1 (0.48) ALDH1A1EGLN2KDM4EGAACA12
Sulfuric Acid SCHEMBL29261683 0.89 CA1 (0.46) ALDH1A1EGLN2KDM4EGAACA12
Acetic Acid SCHEMBL29261715 0.86 FFAR1 (0.40) ALDH1A1EGLN2KDM4EGAAMEN1
SCHEMBL4047375 0.84 KIF11 (0.59) ALDH1A1EGLN2CA12CA1CA2
SCHEMBL29726475 0.82 ALDH1A1 (0.46) ALDH1A1EGLN2KDM4EGAACA12
SCHEMBL568906 0.82 ALDH1A1 (0.46) ALDH1A1EGLN2KDM4EGAACA12
Sulfuric Acid SCHEMBL29261717 0.82 CA12 (0.40) ALDH1A1EGLN2CA12CA1CA2
SCHEMBL229147 0.78 EGLN2 (0.44) ALDH1A1EGLN2KDM4EGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945917-A Preparation method of 3-fluoro-4-nitrobenzoic acid 衢州康鹏化学有限公司 2024-04-30 CN claimed
CN-117447327-A Preparation method of 3-fluoro-4-nitrobenzoic acid 上海万溯药业有限公司 2024-01-26 CN claimed
CN-116375549-A Method and system for synthesizing amide compound from nitrile compound 深圳湾实验室 2023-07-04 CN claimed
CN-111668481-B Preparation method of metal aluminum secondary battery with multi-group organic micromolecules as positive electrode 北京科技大学 2021-12-03 CN claimed
CN-109678741-B Preparation method of 4-amino-3-fluorobenzoic acid 金凯(辽宁)生命科技股份有限公司 2021-11-30 CN claimed
CN-111668481-A Preparation method of metal aluminum secondary battery with multi-group organic micromolecules as positive electrode 北京科技大学 2020-09-15 CN claimed
CN-109096783-A A kind of environment-friendly modified isocyanate resin water-based emulsion and its manufacturing method 广州木森态新材料科技有限公司 2018-12-28 CN claimed
EP-2906559-B1 AZAINDOLINES HOFFMANN LA ROCHE (CH) 2017-02-08 EP claimed
US-9309248-B2 Azaindolines HOFFMANN-LA ROCHE INC. (US) 2016-04-12 US claimed
US-20150266879-A1 AZAINDOLINES HOFFMANN-LA ROCHE INC. 2015-09-24 US claimed
EP-2906559-A1 AZAINDOLINES F. Hoffmann-La Roche AG (CH) 2015-08-19 EP claimed
WO-2014056871-A1 AZAINDOLINES F. HOFFMANN-LA ROCHE AG (CH) 2014-04-17 WO claimed
EP-3887359-B1 NOVEL TETRAZINE COMPOUNDS FOR IN VIVO IMAGING UNIV COPENHAGEN (DK) 2026-05-06 EP disclosed
WO-2026088070-A1 COMPOUNDS PFIZER INC. (US) 2026-04-30 WO disclosed
US-20260090265-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGE SENSOR, PHOTOSENSOR AND SOLID-STATE IMAGING APPARATUS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-03-26 US disclosed
US-12534463-B2 Substituted tricyclic compounds as FGFR inhibitors INCYTE CORPORATION (US) 2026-01-27 US disclosed
US-4120693-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-17 US disclosed
US-4111681-A CYCLOALKANAPYRAZOLE-3-CARBONITRILE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-05 US disclosed
US-4108628-A Cycloalkanopyrazole herbicides mixtures E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-22 US disclosed
US-4059434-A Cycloalkanapyrazole herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266879-A1 AZAINDOLINES AZI2, H1-5, CCNY ALDH1A1 682/4885EGLN2 3233/4885KDM4E 161/4885
US-12534463-B2 Substituted tricyclic compounds as FGFR inhibitors FGFR3, FGFR1, FGFR4 ALDH1A1 2330/4885EGLN2 3871/4885KDM4E 756/4885
US-20260090265-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGE SENSOR, PHOTOSENSOR AND SOLID-STATE IMAGING APPARATUS SLC43A1, CNPY2, SCO2 ALDH1A1 2453/4885EGLN2 953/4885KDM4E 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.