SCHEMBL16587386

SCHEMBL16587386

Cc1ccc(S(=O)(=O)NC(=O)NC(N)=S)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA9 Q16790 3/20 0.56
CA12 O43570 2/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA7 P43166 1/20 0.56
CA13 Q8N1Q1 1/20 0.56
CA14 Q9ULX7 1/20 0.56
LMNA P02545 4/20 0.55
KMT2A Q03164 1/20 0.54
HTT P42858 1/20 0.53
TP53 P04637 2/20 0.52
TSHR P16473 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ALB P02768 1/20 0.52
CYP2C9 P11712 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7363066 0.84 ALDH1A1 (0.60) ALDH1A1CA1CA2CA9CA12
SCHEMBL8712446 0.84 ALDH1A1 (0.67) ALDH1A1CA1CA2CA9CA12
SCHEMBL5184740 0.82 LMNA (0.69) ALDH1A1CA1CA2CA9CA12
SCHEMBL28633918 0.80 CA1 (0.62) ALDH1A1CA1CA2CA9CA12
SCHEMBL170426 0.79 CA1 (0.59) ALDH1A1CA1CA2CA9CA12
Hydrochloric Acid SCHEMBL5117449 0.78 CA1 (0.60) ALDH1A1CA1CA2CA9CA12
SCHEMBL4742655 0.78 LMNA (0.63) ALDH1A1CA1CA2CA9CA12
SCHEMBL9182658 0.76 LMNA (0.76) ALDH1A1CA1CA2CA9CA12
SCHEMBL29135554 0.76 LMNA (0.58) ALDH1A1CA1CA2CA9CA12
SCHEMBL9181455 0.75 ALDH1A1 (0.62) ALDH1A1CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3612609-B1 ADHESIVE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2022-12-28 EP disclosed
US-20210171810-A1 Two Step Adhesive System HENKEL AG & CO. KGAA (DE) 2021-06-10 US disclosed
US-20210163799-A1 Two-Part, Cyanoacrylate/Free Radically Curable Adhesive Systems HENKEL AG & CO. KGAA (DE) 2021-06-03 US disclosed
US-10590311-B2 Accelerators for two part curable compositions Henkel IP & Holding GmbH (DE) 2020-03-17 US disclosed
WO-2020035580-A1 TWO STEP ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2020-02-20 WO disclosed
WO-2020037195-A1 TWO-PART, CYANOACRYLATE/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2020-02-20 WO disclosed
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed