Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | IGF2R | P11717 | 2/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16869952 | 1.00 | AMY1A (0.47) | AMY1AIGF2RSELESTAT3ALDH1A1 | |
| SCHEMBL14616228 | 0.96 | AMY1A (0.44) | AMY1AIGF2RSELESTAT3ALDH1A1 | |
| SCHEMBL19480148 | 0.93 | IGF2R (0.46) | AMY1AIGF2RSELESTAT3ALDH1A1 | |
| SCHEMBL19480247 | 0.93 | IGF2R (0.46) | AMY1AIGF2RSELESTAT3ALDH1A1 | |
| SCHEMBL26032277 | 0.90 | AMY1A (0.54) | AMY1AIGF2RSELESTAT3ALDH1A1 | |
| SCHEMBL27279098 | 0.89 | AMY1A (0.51) | AMY1AIGF2RSELESTAT3 | |
| SCHEMBL19480243 | 0.88 | IGF2R (0.42) | AMY1AIGF2RSELESTAT3ALDH1A1 | |
| SCHEMBL22026382 | 0.88 | IGF2R (0.48) | AMY1AIGF2RSELESTAT3PTPN1 | |
| SCHEMBL16866291 | 0.85 | AMY1A (0.41) | AMY1AIGF2RSELESTAT3ALDH1A1 | |
| SCHEMBL24250552 | 0.84 | SELE (0.45) | AMY1AIGF2RSELESTAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987217-B2 | Modified saponins for the treatment of fungal infections | THE GENERAL HOSPITAL CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |